Evidence map›Paper›PMID 33987830›Full record

ArticleImmunology2021

Gm40600 promotes CD4

Youdi He, Ying Fang, Bing Zhai, Xiaoling Liu, Gaizhi Zhu, Shan Zhou, Yaqi Xu, Xiaoqian Wang, Wenting Su, Renxi Wang

Open access · bronzeAbstract read
In one paragraph

Article in Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

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  7. Gm40600 promotes CD4Immunology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Youdi HeBeijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China.
Ying FangDepartment of Rheumatology, First Hospital of Jilin University, Changchun, China.
Bing ZhaiDepartment of Geriatric Hematology, Chinese PLA General Hospital, Beijing, China.
Xiaoling LiuDepartment of Dermatology, First Medical Centre of Chinese, PLA General Hospital, Beijing, China.
Gaizhi ZhuBeijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China.
Shan ZhouBeijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China.
Yaqi XuBeijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China.
Xiaoqian WangStaidson (Beijing) Biopharmaceuticals Co. Ltd, Beijing, China.
Wenting SuBeijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China.
Renxi WangBeijing Institute of Brain Disorders, Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders, Capital Medical University, Beijing, China.ORCID 0000-0003-4130-3334
Capital Medical University · CNChinese PLA General Hospital · CNBeijing VDJBio (China) · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is important to characterize novel proteins involved in T- and B-cell responses. Our previous study demonstrated that a novel protein, Mus musculus Gm40600, reduced the proliferation of Mus musculus plasmablast (PB)-like SP 2/0 cells and B-cell responses induced in vitro by LPS. In the present study, we revealed that Gm40600 directly promoted CD4

Indexed as

AnimalsB-LymphocytesCalcium SignalingCD4-Positive T-LymphocytesCell DifferentiationCell ProliferationCells, CulturedCytokinesImmunity, HumoralImmunomodulationIntracellular Signaling Peptides and ProteinsLeukemia Virus, MurineLymphocyte ActivationMembrane ProteinsMiceMice, Inbred C57BLAhnak protein, mouseCytokinesGm40600 protein, mouseIntracellular Signaling Peptides and ProteinsMembrane ProteinsNeoplasm ProteinsRNA-Directed DNA PolymeraseAhnakB cellsCD4+ T cellsGm40600Th cells

Identifiers

PMID33987830
PMCPMC8358717
OpenAlexW3163461992

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.