ArticleArchives of virology2021
Retrospective surveillance of porcine circovirus 4 in pigs in Inner Mongolia, China, from 2016 to 2018.
Article in Archives of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
33 citing papers in PubMed, 39 citations in OpenAlex.
- Porcine circovirus 4 status of domestic pigs and wild animals in Poland.Journal of veterinary research · 2026Article
- Epidemiological Survey of Porcine Circovirus Types 2 and 3 in Liaoning Region of China and Preparation of Monoclonal Antibodies Against PCV3 Cap Protein.Veterinary sciences · 2026Article
- Significant Detection of Porcine Circovirus 3 and Porcine Circovirus 4 in Wild Boars from Mid-Western Spain Without Apparent Sanitary Consequences.Animals : an open access journal from MDPI · 2025Article
- Development and Evaluation of an Immunochromatographic Strip and a Magnetic Chemiluminescence Immunoassay for Detection ofVeterinary sciences · 2025Article
- Retrospective Study Reveals Decades of PCV4 Circulation in Spain.Transboundary and emerging diseases · 2025Article
- Comparative Pathogenicity of PCV2, PCV3, and PCV4 in Piglets: Insights Into Clinical, Pathological, and Immunological Features.Transboundary and emerging diseases · 2025Article
- Article
- Editorial - The importance of porcine viruses to human health - a collection.Archives of virology · 2024Article
- First detection of PCV4 in swine in the United States: codetection with PCV2 and PCV3 and direct detection within tissues.Scientific reports · 2024Article
- Molecular detection and genetic characteristics of porcine circovirus 3 and porcine circovirus 4 in central China.Archives of virology · 2024Article
- First molecular detection and genetic characterization of porcine circovirus 4 in the Gansu Province of China.PloS one · 2024Article
- The Prevalence and Genetic Diversity of Porcine Circoviruses (PCVs) during 2017-2023 in Guangdong Province, China.Animals : an open access journal from MDPI · 2023Article
- Epizootiological surveillance of porcine circoviruses in free-ranging wild boars in China.Virologica Sinica · 2023Article
- Development of a droplet digital PCR method for detection of porcine circovirus 4.BMC veterinary research · 2023Article
- Molecular detection and genetic characterization of porcine circovirus 4 (PCV4) in Thailand during 2019-2020.Scientific reports · 2023Article
- First report on identification and genomic analysis of a novel porcine circovirus (porcine circovirus 4) in cats.Frontiers in microbiology · 2023Article
- Development of a TaqMan-Probe-Based Multiplex Real-Time PCR for the Simultaneous Detection of Porcine Circovirus 2, 3, and 4 in East China from 2020 to 2022.Veterinary sciences · 2022Article
- First Identification and Phylogenetic Analysis of Porcine Circovirus Type 4 in Fur Animals in Hebei, China.Animals : an open access journal from MDPI · 2022Article
- Phylodynamic analysis of current Porcine circovirus 4 sequences: Does the porcine circoviruses evolutionary history repeat itself?Transboundary and emerging diseases · 2022Article
- Genetic Variation Analysis of Porcine Circovirus Type 4 in South China in 2019 to 2021.Viruses · 2022Article
Corrections and comments
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Authors and funding
17 authors at 5 institutions in 1 country.
Funding
Abstract
A novel circovirus designated "porcine circovirus type 4" (PCV4) was recently reported in pigs with severe clinical disease in Hunan Province, China. Relatively little is known about the molecular epidemiology of this recently discovered virus. In order to assess the prevalence of PCV4 infection in pigs and to analyze its genomic characteristics, 1683 clinical samples were collected in Inner Mongolia, China, from 2016 to 2018. The overall infection rate of PCV4 was 1.6% (27/1683) at the sample level and 21.6% (11/51) at the farm level, with rates ranging from 3.2% (1/31) to 20.0% (6/30) on different PCV4-positive pig farms. In addition, the PCV4 infection rates at both the sample and farm level increased from 2016 to 2018. This also showed that PCV4 was present in pigs in 2016 in China and therefore did not arrive later than this date. Additionally, our findings showed that PCV4 infections had no association with PCV2 or PCV3 infections. We sequenced the complete genomes of three PCV4 strains and found that the PCV4 strains had a high degree of genetic stability but shared less than 80% sequence identity with other circoviruses. We identified six amino acid mutations in the Rep protein and seven in the Cap protein. Phylogenetic analysis based on Cap and Rep sequences confirmed that the PCV4 strains grouped in an independent branch. Our findings provide important information about the prevalence and genetic characteristics of PCV4 strains.
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