Evidence map›Paper›PMID 33987732›Full record

ArticleLasers in medical science2022

Effect of antimicrobial photodynamic therapy with red led and methylene blue on the reduction of halitosis: controlled microbiological clinical trial.

Ana Carolina Costa da Mota, Marcela Leticia Leal Gonçalves, Anna Carolina Ratto Tempestini Horliana, Alessandro Melo Deana, Lisyanne Araújo de Souza Cavalcante, Andréa Oliver Gomes, Marcia Pinto Alves Mayer, Ellen Sayuri Ando Suguimoto, Kristianne Porta Santos Fernandes, Raquel Agnelli Mesquita-Ferrari and 3 more

Registry-linked trialAbstract readControlled Clinical Trial
PubMed Publisher
In one paragraph

Article in Lasers in medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07463859 (Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus), which is not on this map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07463859 narecruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus: A Randomized Clinical Trial

TypeinterventionalSponsorUniversity of Sao PauloRan2026 to 2027Enrolled32ConditionsType 2 Diabetes, Halitosis, PeriodontitisArmsScaling and root planing, Photodynamic Therapy with Conventional Methylene Blue
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Ana Carolina Costa da MotaPostgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, Vergueiro Street, 235/249, Liberdade, São Paulo, SP, ZIP 01504-001, Brazil.
Marcela Leticia Leal GonçalvesPostgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, Vergueiro Street, 235/249, Liberdade, São Paulo, SP, ZIP 01504-001, Brazil.
Anna Carolina Ratto Tempestini HorlianaPostgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, Vergueiro Street, 235/249, Liberdade, São Paulo, SP, ZIP 01504-001, Brazil.
Alessandro Melo DeanaPostgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, Vergueiro Street, 235/249, Liberdade, São Paulo, SP, ZIP 01504-001, Brazil.
Lisyanne Araújo de Souza CavalcantePostgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, Vergueiro Street, 235/249, Liberdade, São Paulo, SP, ZIP 01504-001, Brazil.
Andréa Oliver GomesPostgraduation Program in Rehabilitation Sciences, Universidade Nove de Julho, Vergueiro Street, 235/249, Liberdade, São Paulo, SP, ZIP 01504-001, Brazil.
Marcia Pinto Alves MayerMicrobiology ICB, Universidade de São Paulo, Butanta, São Paulo, SP, Brazil.
Ellen Sayuri Ando SuguimotoMicrobiology ICB, Universidade de São Paulo, Butanta, São Paulo, SP, Brazil.
Kristianne Porta Santos FernandesPostgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, Vergueiro Street, 235/249, Liberdade, São Paulo, SP, ZIP 01504-001, Brazil.
Raquel Agnelli Mesquita-FerrariPostgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, Vergueiro Street, 235/249, Liberdade, São Paulo, SP, ZIP 01504-001, Brazil.
Renato Araújo PratesPostgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, Vergueiro Street, 235/249, Liberdade, São Paulo, SP, ZIP 01504-001, Brazil.
Lara Jansiski MottaPostgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, Vergueiro Street, 235/249, Liberdade, São Paulo, SP, ZIP 01504-001, Brazil.
Sandra Kalil BussadoriPostgraduation Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho, Vergueiro Street, 235/249, Liberdade, São Paulo, SP, ZIP 01504-001, Brazil. sandra.skb@gmail.com.ORCID http://orcid.org/0000-0002-9853-1138
Universidade Nove de Julho · BRUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To determine the effect of antimicrobial photodynamic therapy (aPDT) using a red light-emitting diode (LED) on the reduction of halitosis and microbiological levels in the tongue coating immediately after irradiation, 7, 14, and 30 days after treatment. Forty-five young adults diagnosed with halitosis were allocated to three groups: G1, aPDT with 0.005% methylene blue and red LED (660 nm, four irradiation points, 90 s per point, power of 400 mW, 36 J per point, radiant exposure of 95 J/cm

Indexed as

Anti-Infective AgentsHalitosisPhotochemotherapyHumansMethylene BluePhotosensitizing AgentsRNA, Ribosomal, 16SYoung AdultAnti-Infective AgentsMethylene BluePhotosensitizing AgentsRNA, Ribosomal, 16SAntimicrobial photodynamic therapyClinical trialHalitosisLED

Identifiers

PMID33987732
OpenAlexW3161544817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.