Evidence map›Paper›PMID 33987632›Full record

ArticleChemical communications (Cambridge, England)2021

An alginate-confined peroxygenase-CLEA for styrene epoxidation.

Friederike E H Nintzel, Yinqi Wu, Matteo Planchestainer, Martin Held, Miguel Alcalde, Frank Hollmann

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical communications (Cambridge, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Friederike E H NintzelDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629 HZ, Delft, The Netherlands. f.hollmann@tudelft.nl.ORCID http://orcid.org/0000-0002-0637-4383
Yinqi WuDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629 HZ, Delft, The Netherlands. f.hollmann@tudelft.nl.ORCID http://orcid.org/0000-0002-6158-8288
Matteo PlanchestainerDepartment of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, Basel 4058, Switzerland.ORCID http://orcid.org/0000-0002-9938-5451
Martin HeldDepartment of Biosystems Science and Engineering, ETH Zürich, Mattenstrasse 26, Basel 4058, Switzerland.
Miguel AlcaldeDepartment of Biocatalysis, Institute of Catalysis and Petrochemistry (CSIC), Madrid, Spain.
Frank HollmannDepartment of Biotechnology, Delft University of Technology, van der Maasweg 9, 2629 HZ, Delft, The Netherlands. f.hollmann@tudelft.nl.ORCID http://orcid.org/0000-0003-4821-756X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxyfunctionalisation reactions in neat substrate still pose a challenge for biocatalysis. Here, we report an alginate-confined peroxygenase-CLEA to catalyse the enantioselective epoxidation of cis-β-methylstyrene in a solvent-free reaction system achieving turnover numbers of 96 000 for the biocatalyst and epoxide concentrations of 48 mM.

Identifiers

PMID33987632
PMCPMC8191455

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.