Evidence map›Paper›PMID 33987558›Full record

ArticleJournal of animal science and technology2020

Mechanistic insight into the progressive retinal atrophy disease in dogs

Sunirmal Sheet, Srikanth Krishnamoorthy, Woncheoul Park, Dajeong Lim, Jong-Eun Park, Minjeong Ko, Bong-Hwan Choi

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of animal science and technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sunirmal SheetAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Korea.ORCID https://orcid.org/0000-0001-6989-1292
Srikanth KrishnamoorthyAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Korea.ORCID https://orcid.org/0000-0002-5205-193X
Woncheoul ParkAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Korea.ORCID https://orcid.org/0000-0003-3140-5628
Dajeong LimAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Korea.ORCID https://orcid.org/0000-0003-3966-9150
Jong-Eun ParkAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Korea.ORCID https://orcid.org/0000-0003-0718-3463
Minjeong KoAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Korea.ORCID https://orcid.org/0000-0002-8603-3764
Bong-Hwan ChoiAnimal Genomics and Bioinformatics Division, National Institute of Animal Science, Rural Development Administration, Wanju 55365, Korea.ORCID https://orcid.org/0000-0002-4795-3285
Rural Development Administration · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The retinal degenerative disease, progressive retinal atrophy (PRA) is a major reason of vision impairment in canine population. Canine PRA signifies an inherently dissimilar category of retinal dystrophies which has solid resemblances to human retinis pigmentosa. Even though much is known about the biology of PRA, the knowledge about the intricate connection among genetic loci, genes and pathways associated to this disease in dogs are still remain unknown. Therefore, we have performed a genome wide association study (GWAS) to identify susceptibility single nucleotide polymorphisms (SNPs) of PRA. The GWAS was performed using a case-control based association analysis method on PRA dataset of 129 dogs and 135,553 markers. Further, the gene-set and pathway analysis were conducted in this study. A total of 1,114 markers associations with PRA trait at

Indexed as

CanineGene ontologyGenome wide association study (GWAS)Inherited diseaseKyoto Encyclopedia of Genes and Genomes (KEGG) pathwaysProgressive retinal atrophy

Identifiers

PMID33987558
PMCPMC7721568
OpenAlexW3111780788

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.