ReviewAnnals of translational medicine2021
A narrative review of changes in microvascular permeability after burn.
Review in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- Coenzyme Q10 supplementation in burn patients: a double-blind placebo-controlled randomized clinical trial.Trials · 2024Trial
- Burn-associated metabolic dysfunction: could extracellular vesicles play a role?Clinical science (London, England : 1979) · 2026Review
- Analysis of treatment pathways and long-term prevalence of pruritus after burn - An observational study with real-world data.Burns : journal of the International Society for Burn Injuries · 2026Observational
- Cellular and molecular changes in the skin driving increased nociception and pain during burn injury and repair.Frontiers in pain research (Lausanne, Switzerland) · 2026Review
- Burns: The "Fuse" That Ignites Organ Crisis - A Narrative Review of Mechanisms and Crosstalk in Post-Burn MODS.Journal of inflammation research · 2026Review
- A predictive formula for the indication of airway management in burn patients.European journal of medical research · 2025Article
- Histological efficacy of high-dose intravenous vitamin C infusion in severely burned patients.Journal of molecular histology · 2025Article
- Pilot Study on Resuscitation Volume's Effect on Perfusion and Inflammatory Cytokine Expression in Peri-Burn Skin: Implications for Burn Conversion.European burn journal · 2025Article
- Efficacy of multimodal rehabilitation strategies on gastrointestinal function recovery in postoperative aortic dissection patients: a narrative review.Frontiers in physiology · 2025Review
- Conditional deficiency of Rho-associated kinases disrupts endothelial cell junctions and impairs respiratory function in adult mice.FEBS open bio · 2024Article
- Acute kidney injury in patients with burns.Nature reviews. Nephrology · 2024Review
- Effect of sugammadex on postoperative complications in patients with severe burn who underwent surgery: a retrospective study.Scientific reports · 2024Article
- Thermal Imaging as a Method to Indirectly Assess Peripheral Vascular Integrity and Tissue Viability in Veterinary Medicine: Animal Models and Clinical Applications.Animals : an open access journal from MDPI · 2023Review
- Knowledge and Attitudes in First Aid Practices for Thermal Burns: a Cross-sectional Study Among Adults in Northern Greece.Materia socio-medica · 2023Article
- [Research advances on severe burn infection and cytokine storm].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2023Review
- Pathological changes in the brain after peripheral burns.Burns & trauma · 2023Review
- The effects of different stress on intestinal mucosal barrier and intestinal microecology were discussed based on three typical animal models.Frontiers in cellular and infection microbiology · 2022Review
- Research progress on risk factors of delirium in burn patients: A narrative review.Frontiers in psychiatry · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe aimed to review and discuss some of the latest research results related to post-burn pathophysiological changes and provide some clues for future study.
backgroundBurns are one of the most common and serious traumas and consist of a series of pathophysiological changes of thermal injury. Accompanied by thermal damage to skin and soft tissues, inflammatory mediators are released in large quantities. Changes in histamine, bradykinin, and cytokines such as vascular endothelial growth factor (VEGF), metabolic factors such as adenosine triphosphate (ATP), and activated neutrophils all affect the body's vascular permeability.
methodsWe searched articles with subject words "microvascular permeability", "burn" "endothelium", and "endothelial barrier" in PubMed in English published from the beginning of database to Dec, 2020.
conclusionsThe essence of burn shock is the rapid and extensive fluid transfer in burn and non-burn tissue. After severe burns, the local and systemic vascular permeability increase, causing intravascular fluid extravasation, leading to a progressive decrease in effective circulation volume, an increase in systemic vascular resistance, a decrease in cardiac output, peripheral tissue edema, multiple organ failure, and even death. There are many cells, tissues, mediators and structures involved in the pathophysiological process of the damage to vascular permeability. Ulinastatin is a promising agent for this problem.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.