Evidence map›Paper›PMID 33987368›Full record

ArticleAnnals of translational medicine2021

Metastasis-associated gene 1 (MTA1) enhances cisplatin resistance of malignant pleural mesothelioma by ATR-Chk1-mediated DNA repair.

Caihua Xu, Yufeng Hu, Bin Chen, Dapeng Li, Rongrui Liang, Meng Shen, Mengyao Wu, Min Tao

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Caihua XuDepartment of Oncology of the First Affiliated Hospital of Soochow University, Suzhou, China.
Yufeng HuDepartment of Oncology of the First Affiliated Hospital of Soochow University, Suzhou, China.
Bin ChenDepartment of Cardiovascular Surgery, Wuxi No. 2 People's Hospital, Wuxi, China.
Dapeng LiDepartment of Oncology of the First Affiliated Hospital of Soochow University, Suzhou, China.
Rongrui LiangDepartment of Oncology of the First Affiliated Hospital of Soochow University, Suzhou, China.
Meng ShenDepartment of Oncology of the First Affiliated Hospital of Soochow University, Suzhou, China.
Mengyao WuDepartment of Oncology of the First Affiliated Hospital of Soochow University, Suzhou, China.
Min TaoDepartment of Oncology of the First Affiliated Hospital of Soochow University, Suzhou, China.
Soochow University · CNFirst Affiliated Hospital of Soochow University · CNWuxi No.2 People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMalignant pleural mesothelioma (MPM) chemoresistance remains a challenge to oncologists. In our previous study, we demonstrated that the aberrant expression of metastasis-associated gene 1 (

methodsWestern blotting and real-time polymerase chain reaction were used to analyze the protein and mRNA levels. A stable clone with a knockdown of

resultsThe

conclusionsThese data suggest that

Indexed as

ATR-Chk1chemoresistancemalignant pleural mesothelioma (MPM)Metastasis-associated gene 1 (MTA1)

Identifiers

PMID33987368
PMCPMC8106096
OpenAlexW3157681422

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.