Evidence map›Paper›PMID 33986901›Full record

ArticleBiomicrofluidics2021

Adoption of reinforcement learning for the intelligent control of a microfluidic peristaltic pump.

Takaaki Abe, Shinsuke Oh-Hara, Yoshiaki Ukita

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Article in Biomicrofluidics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Takaaki AbeDepartment of Engineering, Integrated Graduate School of Medicine, Engineering, and Agricultural Sciences, University of Yamanashi, 4-3-11 Takeda, Kofu 400-8510, Japan.ORCID 0000-0001-9317-6512
Shinsuke Oh-HaraGraduate Faculty of Interdisciplinary Research, University of Yamanashi, 4-3-11 Takeda, Kofu 400-8510, Japan.ORCID 0000-0001-7155-4690
Yoshiaki UkitaGraduate Faculty of Interdisciplinary Research, University of Yamanashi, 4-3-11 Takeda, Kofu 400-8510, Japan.ORCID 0000-0002-3267-6940

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We herein report a study on the intelligent control of microfluidic systems using reinforcement learning. Integrated microvalves are utilized to realize a variety of microfluidic functional modules, such as switching of flow pass, micropumping, and micromixing. The application of artificial intelligence to control microvalves can potentially contribute to the expansion of the versatility of microfluidic systems. As a preliminary attempt toward this motivation, we investigated the application of a reinforcement learning algorithm to microperistaltic pumps. First, we assumed a Markov property for the operation of diaphragms in the microperistaltic pump. Thereafter, components of the Markov decision process were defined for adaptation to the micropump. To acquire the pumping sequence, which maximizes the flow rate, the reward was defined as the obtained flow rate in a state transition of the microvalves. The present system successfully empirically determines the optimal sequence, which considers the physical characteristics of the components of the system that the authors did not recognize. Therefore, it was proved that reinforcement learning could be applied to microperistaltic pumps and is promising for the operation of larger and more complex microsystems.

Identifiers

PMID33986901
PMCPMC8106535

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.