Evidence map›Paper›PMID 33986885›Full record

ArticlePrzeglad gastroenterologiczny2021

Effects of sildenafil citrate on pancreatic and lung complications in an experimental L-arginine-induced acute pancreatitis model.

Baris Gulturk, Ahmet Bozdag, Refik Ayten, Ziya Cetinkaya, Cuneyt Kirkil, Erhan Aygen, Bilal Ustundag, Ibrahim Hanifi Ozercan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Przeglad gastroenterologiczny, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Baris GulturkDepartment of General Surgery, Elazig Health Application and Research Centre, Health Sciences University, Elazig, Turkey.
Ahmet BozdagDepartment of General Surgery, Faculty of Medicine, Firat University, Elazig, Turkey.
Refik AytenDepartment of General Surgery, Faculty of Medicine, Firat University, Elazig, Turkey.
Ziya CetinkayaDepartment of General Surgery, Faculty of Medicine, Firat University, Elazig, Turkey.
Cuneyt KirkilDepartment of General Surgery, Faculty of Medicine, Firat University, Elazig, Turkey.
Erhan AygenDepartment of General Surgery, Faculty of Medicine, Firat University, Elazig, Turkey.
Bilal UstundagDepartment of Biochemistry, School of Medicine, Firat University, Elazig, Turkey.
Ibrahim Hanifi OzercanDepartment of Pathology, School of Medicine, Firat University, Elazig, Turkey.
Fırat University · TRSağlık Bilimleri Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimIn this study, we aimed to investigate the effects of sildenafil citrate on acute pancreatitis and pulmonary complications of the disease. MATERIAL AND

methodsIn this study, we used 21 male Wistar-Albino rats weighing between 185 and 230 g. The rats were divided into 3 groups. Group 1 rats (control group,

resultsIn the treatment group, levels of amylase, AST, ALT, LDH, IL-1, IL-6, TNF-α, and NO were lower. In addition, pancreas and lung oedema, and perivascular inflammation were significantly less on histopathological examination when compared to the study group (

conclusionsSildenafil citrate significantly decreases various biochemical and histopathological changes in the early phase of acute pancreatitis and protects pancreatic tissue.

Indexed as

acute pancreatitisL-argininepancreatitis complicationssildenafil

Identifiers

PMID33986885
PMCPMC8112277
OpenAlexW3157669986

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.