Evidence map›Paper›PMID 33986745›Full record

ReviewFrontiers in immunology2021

Mechanisms Used by Probiotics to Confer Pathogen Resistance to Teleost Fish.

Rocío Simón, Félix Docando, Noelia Nuñez-Ortiz, Carolina Tafalla, Patricia Díaz-Rosales

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
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  6. Review
  7. Article
  8. Dietary Encapsulation of a NovelAntioxidants (Basel, Switzerland) · 2026
    Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Genomic Sequence ofVeterinary sciences · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Immunomodulatory properties ofFrontiers in immunology · 2024
    Article
  20. Dietary supplementation ofFish and shellfish immunology reports · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rocío SimónFish Immunology and Pathology Laboratory, Animal Health Research Centre (CISA-INIA), Madrid, Spain.
Félix DocandoFish Immunology and Pathology Laboratory, Animal Health Research Centre (CISA-INIA), Madrid, Spain.
Noelia Nuñez-OrtizFish Immunology and Pathology Laboratory, Animal Health Research Centre (CISA-INIA), Madrid, Spain.
Carolina TafallaFish Immunology and Pathology Laboratory, Animal Health Research Centre (CISA-INIA), Madrid, Spain.
Patricia Díaz-RosalesFish Immunology and Pathology Laboratory, Animal Health Research Centre (CISA-INIA), Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Probiotics have been defined as live microorganisms that when administered in adequate amounts confer health benefits to the host. The use of probiotics in aquaculture is an attractive bio-friendly method to decrease the impact of infectious diseases, but is still not an extended practice. Although many studies have investigated the systemic and mucosal immunological effects of probiotics, not all of them have established whether they were actually capable of increasing resistance to different types of pathogens, being this the outmost desired goal. In this sense, in the current paper, we have summarized those experiments in which probiotics were shown to provide increased resistance against bacterial, viral or parasitic pathogens. Additionally, we have reviewed what is known for fish probiotics regarding the mechanisms through which they exert positive effects on pathogen resistance, including direct actions on the pathogen, as well as positive effects on the host.

Indexed as

Animal FeedAnimalsAquacultureDisease ResistanceFish DiseasesFishesProbioticsimmunomodulatory effectinterference mechanismspathogen resistanceprobioticsteleosts

Identifiers

PMID33986745
PMCPMC8110931

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.