Evidence map›Paper›PMID 33986739›Full record

ArticleFrontiers in immunology2021

Programmed Death-Ligand 1 Expression Potentiates the Immune Modulatory Function Of Myeloid-Derived Suppressor Cells in Systemic Lupus Erythematosus.

Min-Jung Park, Jin-Ah Baek, Jeong Won Choi, Se Gwang Jang, Da-Som Kim, Sung-Hwan Park, Mi-La Cho, Seung-Ki Kwok

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Myeloid-Derived Suppressor Cells in Inflammatory Arthritis.International journal of molecular sciences · 2026
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Progression of mCell death discovery · 2024
    Review
  8. Review
  9. Here, There, and Everywhere: Myeloid-Derived Suppressor Cells in Immunology.Journal of immunology (Baltimore, Md. : 1950) · 2023
    Review
  10. Review
  11. Crosstalk among mJournal of hematology & oncology · 2022
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Min-Jung ParkThe Rheumatism Research Center, The Catholic University of Korea, Seoul, South Korea.
Jin-Ah BaekThe Rheumatism Research Center, The Catholic University of Korea, Seoul, South Korea.
Jeong Won ChoiThe Rheumatism Research Center, The Catholic University of Korea, Seoul, South Korea.
Se Gwang JangThe Rheumatism Research Center, The Catholic University of Korea, Seoul, South Korea.
Da-Som KimThe Rheumatism Research Center, The Catholic University of Korea, Seoul, South Korea.
Sung-Hwan ParkThe Rheumatism Research Center, The Catholic University of Korea, Seoul, South Korea.
Mi-La ChoThe Rheumatism Research Center, The Catholic University of Korea, Seoul, South Korea.
Seung-Ki KwokThe Rheumatism Research Center, The Catholic University of Korea, Seoul, South Korea.
Catholic University of Korea · KRSeoul St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple studies have explored the potential role of programmed death-ligand 1 (PD-L1) as a mediator of Myeloid-derived suppressor cells (MDSCs) effects in various cancers. However, the role PD-L1 expression in MDSCs on autoimmune disease is still largely unknown.This study was undertaken to whether MDSC expressing PD-L1 have more potent immunoregulatory activity and control autoimmunity more effectively in two murine models of lupus (MRL/

Indexed as

Gene Expression RegulationAnimalsAutoimmunityB7-H1 AntigenBiomarkersB-Lymphocyte SubsetsCell- and Tissue-Based TherapyDisease Models, AnimalDisease SusceptibilityFemaleHumansImmunomodulationImmunophenotypingLupus Erythematosus, SystemicMiceMice, Inbred MRL lprB7-H1 AntigenBiomarkersCD274 protein, humancell therapymyeloid-derived suppressor cellsprogrammed death-ligand 1regulatory B cellssystemic lupus erythematosus

Identifiers

PMID33986739
PMCPMC8110929
OpenAlexW3157182374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.