ReviewFrontiers in systems neuroscience2021
Developing Proprioceptive Countermeasures to Mitigate Postural and Locomotor Control Deficits After Long-Duration Spaceflight.
Review in Frontiers in systems neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- The measurement of proprioceptive accuracy: A systematic literature review.Journal of sport and health science · 2023Pooled it
- Spaceflight and sport science: Physiological monitoring and countermeasures for the astronaut-athlete on Mars exploration missions.Experimental physiology · 2026Review
- Proteograph™-based proteome and sphingolipidome analyses identified novel serum biomarkers to monitor astronauts' health in spaceflight.Frontiers in physiology · 2026Article
- Spaceflight human optimization and performance: positioning astronauts in an operational framework to promote health, fitness, and mission readiness.Frontiers in physiology · 2026Review
- Spaceflight Standard Measures is a multidisciplinary study that systematically monitors risks to astronaut health and performance.NPJ microgravity · 2025Review
- Changes of EEG beta band power and functional connectivity during spaceflight: a retrospective study.Scientific reports · 2025Article
- An examination of ankle joint position sense, postural control and associated neuromuscular deficits in patients with plantar fasciitis: a cross-sectional analysis with advanced biomechanical and psychosocial correlates.Journal of orthopaedic surgery and research · 2025Article
- The effect of combined compression and tactile stimulation on ankle somatosensation in a lunar gravity lower limb load analog.Frontiers in physiology · 2025Article
- Effects of short-duration spaceflight on the execution of critical mission tasks.Frontiers in physiology · 2025Article
- Formaldehyde initiates memory and motor impairments under weightlessness condition.NPJ microgravity · 2024Review
- Functional activities essential for space exploration performed in partial gravity during parabolic flight.NPJ microgravity · 2024Article
- A Pilot Study to Evaluate the Relationships between Supine Proprioception Assessments and Upright Functional Mobility.Brain sciences · 2024Article
- Advancing insights into microgravity induced muscle changes using Caenorhabditis elegans as a model organism.NPJ microgravity · 2024Review
- Systematic review of the effectiveness of standalone passive countermeasures on microgravity-induced physiologic deconditioning.NPJ microgravity · 2024Review
- Development of a ground-based sensorimotor disorientation analog to replicate astronaut postflight experience.Frontiers in physiology · 2024Article
- Effects of intermittent seating upright, lower body negative pressure, and exercise on functional tasks performance after head-down tilt bed rest.Frontiers in physiology · 2024Article
- Impact of Glycemic Control on Shoulder Proprioception in Type 2 Diabetes Mellitus: Mediating the Connection - Insights from a Cross-Sectional Analysis.Journal of multidisciplinary healthcare · 2024Article
- Exploring the Nexus of lower extremity proprioception and postural stability in older adults with osteoporosis: a cross-sectional investigation.Frontiers in public health · 2023Article
- Cognitive and balance functions of astronauts after spaceflight are comparable to those of individuals with bilateral vestibulopathy.Frontiers in neurology · 2023Article
- Tandem Walk in Simulated Martian Gravity and Visual Environment.Brain sciences · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Astronauts experience post-flight disturbances in postural and locomotor control due to sensorimotor adaptations during spaceflight. These alterations may have adverse consequences if a rapid egress is required after landing. Although current exercise protocols can effectively mitigate cardiovascular and muscular deconditioning, the benefits to post-flight sensorimotor dysfunction are limited. Furthermore, some exercise capabilities like treadmill running are currently not feasible on exploration spaceflight vehicles. Thus, new in-flight operational countermeasures are needed to mitigate postural and locomotor control deficits after exploration missions. Data from spaceflight and from analog studies collectively suggest that body unloading decreases the utilization of proprioceptive input, and this adaptation strongly contributes to balance dysfunction after spaceflight. For example, on return to Earth, an astronaut's vestibular input may be compromised by adaptation to microgravity, but their proprioceptive input is compromised by body unloading. Since proprioceptive and tactile input are important for maintaining postural control, keeping these systems tuned to respond to upright balance challenges during flight may improve functional task performance after flight through dynamic reweighting of sensory input. Novel approaches are needed to compensate for the challenges of balance training in microgravity and must be tested in a body unloading environment such as head down bed rest. Here, we review insights from the literature and provide observations from our laboratory that could inform the development of an in-flight proprioceptive countermeasure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.