ArticleFrontiers in neuroscience2021
Comparing the Clinical and Neuropsychological Characteristics of Parkinson's Disease With and Without Freezing of Gait.
Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Botulinum Toxin Effects on Freezing of Gait in Parkinson's Disease: A Systematic Review.Toxins · 2024Pooled it
- Motor planning stage of gait initiation: effects of aging, Parkinson's disease, and associations with cognitive function.Experimental brain research · 2025Article
- Rapid health technology assessment of six non-ergot dopamine-receptor agonists for the treatment of early Parkinson's disease.Frontiers in pharmacology · 2025Article
- Objective assessment of gait and posture symptoms in Parkinson's disease using wearable sensors and machine learning.Frontiers in aging neuroscience · 2025Article
- Analysis of gait characteristics and related factors in patients with Parkinson's disease based on wearable devices.Brain and behavior · 2024Article
- Comparing the efficacy of therapeutic Thai acupressure on plantar acupoints and laser cane therapy on freezing of gait in Parkinson's disease: a randomized non-inferiority trial.Frontiers in neurology · 2024Article
- Association between Cognitive Impairment and Freezing of Gait in Patients with Parkinson's Disease.Journal of clinical medicine · 2023Article
- Retrograde procedural memory is impaired in people with Parkinson's disease with freezing of gait.Frontiers in aging neuroscience · 2023Article
- Effectiveness of Therapies Based on Mirror Neuron System to Treat Gait in Patients with Parkinson's Disease-A Systematic Review.Journal of clinical medicine · 2022Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionFreezing of gait (FOG) is one of the most common walking problems in Parkinson's disease (PD). Impaired cognitive function is believed to play an important role in developing and aggravating FOG in PD. But some evidence suggests that motor function discrepancy may affect testing results. Therefore, we think it is necessary for PD-FOG(+) and PD-FOG(-) patients to complete neuropsychological tests under similar motor conditions.
methodsThis study recruited 44 idiopathic PD patients [PD-FOG(+)
resultsPD patients showed poorer cognitive function, higher risks of depression and anxiety, and more neuropsychiatric symptoms compared with HC. When controlling for age, years of education, and H&Y, there were no statistical differences in cognitive function between PD-FOG(+) and PD-FOG(-) patients. But PD-FOG(+) patients had worse motor and non-motor symptoms than PD-FOG(-) patients. PD patients whose motor symptoms initiated with rigidity and initiated unilaterally were more likely to experience FOG.
conclusionTraditional neuropsychological testing may not be sensitive enough to detect cognitive impairment in PD. Motor symptoms initiated with rigidity and initiated unilaterally might be an important predictor of FOG.
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