ArticleScientific reports2021
A retrospective cohort study of 12,306 pediatric COVID-19 patients in the United States.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 3 of them syntheses that pooled it.
What it found
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The trial behind it
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Who cites it
59 citing papers in PubMed, 3 syntheses or guidelines pooled it, 134 citations in OpenAlex.
- Epidemiology and clinical features of SARS-CoV-2 infection in children and adolescents in the pre-Omicron era: A global systematic review and meta-analysis.Journal of global health · 2024Pooled it
- Neurological Manifestations of Coronavirus Disease 2019 and Mpox in Pediatric Patients and Their Management: A State-of-the-Art Systematic Review.Pediatric neurology · 2023Pooled it
- Taste loss as a distinct symptom of COVID-19: a systematic review and meta-analysis.Chemical senses · 2023Pooled it
- Efficacy of Aspirin Usage in Free Flap Reconstruction of the Head and Neck.Laryngoscope investigative otolaryngology · 2026Article
- Association of Adult Chronic Rhinosinusitis With Pediatric Tonsillectomy and Adenoidectomy.The Laryngoscope · 2026Article
- Outcomes of Head and Neck Free Flap Reconstruction Among Patients With Alcohol Use Disorder.Laryngoscope investigative otolaryngology · 2026Article
- Chronic Rhinosinusitis and Autoimmune Diseases: A Comprehensive Large Population-Based Analysis.Laryngoscope investigative otolaryngology · 2026Article
- A Research Agenda to Mitigate Racial and Ethnic Disparities in U.S. Critical Care Medicine: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2025Article
- Long-Term Impact of the Coronavirus Disease 2019 Pandemic on Children with Eosinophilic Esophagitis.Turkish archives of pediatrics · 2025Article
- Poor Association Between Clinical Characteristics and Seropositivity in Children With Suspected Long COVID-A Single-Centre Study.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Pediatric COVID-19 in Lesotho and Post-pandemic Implications on Lower Respiratory Infections in Children.Cureus · 2024Article
- A cross-sectional study on clinical characteristics and severity of children with COVID-19 admitted to a teaching institute in North India.Journal of family medicine and primary care · 2024Article
- Article
- Clinical Profile and Outcome of Severe Acute Respiratory Illness (SARI) in Children Amidst the COVID-19 Pandemic.Cureus · 2024Article
- Risk Factors for Severe COVID-19 Among Children and Adolescents Enrolled in Acute Respiratory Infection Sentinel Surveillance in South Africa, 2020-2022.Influenza and other respiratory viruses · 2024Article
- Racial and Ethnic Identity and Vulnerability to Upper Respiratory Viral Infections Among US Children.The Journal of infectious diseases · 2024Article
- Understanding Experiences of Youth with Long COVID: A Qualitative Approach.Children (Basel, Switzerland) · 2024Article
- Helmet Ventilation in a Child with COVID-19 and Acute Respiratory Distress Syndrome.Case reports in pediatrics · 2024Article
- Susceptibility of SARS-CoV2 infection in children.European journal of pediatrics · 2023Review
- Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 1 country.
Funding
Abstract
Children and adolescents account for ~ 13% of total COVID-19 cases in the United States. However, little is known about the nature of the illness in children. The reopening of schools underlines the importance of understanding the epidemiology of pediatric COVID-19 infections. We sought to assess the clinical characteristics and outcomes in pediatric COVID-19 patients. We conducted a retrospective cross-sectional analysis of pediatric patients diagnosed with COVID-19 from healthcare organizations in the United States. The study outcomes (hospitalization, mechanical ventilation, critical care) were assessed using logistic regression. The subgroups of sex and race were compared after propensity score matching. Among 12,306 children with lab-confirmed COVID-19, 16.5% presented with respiratory symptoms (cough, dyspnea), 13.9% had gastrointestinal symptoms (nausea, vomiting, diarrhea, abdominal pain), 8.1% had dermatological symptoms (rash), 4.8% had neurological (headache), and 18.8% had other non-specific symptoms (fever, malaise, myalgia, arthralgia and disturbances of smell or taste). In the study cohort, the hospitalization frequency was 5.3%, with 17.6% needing critical care services and 4.1% requiring mechanical ventilation. Following propensity score matching, the risk of all outcomes was similar between males and females. Following propensity score matching, the risk of hospitalization was greater in non-Hispanic Black (RR 1.97 [95% CI 1.49-2.61]) and Hispanic children (RR 1.31 [95% CI 1.03-1.78]) compared with non-Hispanic Whites. In the pediatric population infected with COVID-19, a substantial proportion were hospitalized due to the illness and developed adverse clinical outcomes.
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Registered trials
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