Evidence map›Paper›PMID 33986056›Full record

ArticleBMJ open2021

Launching of the Anaemia Research Peruvian Cohort (ARPEC): a multicentre birth cohort project to explore the iron adaptive homeostasis, infant growth and development in three Peruvian regions.

Doreen Montag, Carlos A Delgado, Consuelo Quispe, David Wareham, Valentina Gallo, Jose Sanchez-Choy, Víctor Sánchez, Ruth Anaya, Elaine Flores, Lorena Roca and 6 more

Abstract readMulticenter Study
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Doreen Montag *Centre for Global Public Health, Queen Mary University of London, London, UK d.montag@qmul.ac.uk.ORCID 0000-0003-1365-1913
Carlos A Delgado *Department of Medicine, Neonatal Intensive Care Unit, Instituto Nacional de Salud del Niño, Lima, Peru.ORCID 0000-0002-6073-8109
Consuelo QuispeSchool of Nursing, Universidad Nacional de San Cristóbal de Huamanga, Ayacucho, Peru.
David WarehamBlizard Institute, Queen Mary University of London, London, UK.
Valentina GalloCentre for Global Public Health, Queen Mary University of London, London, UK.ORCID 0000-0002-1268-8629
Jose Sanchez-ChoyDepartment of Aquaculture and Agroforestry, Universidad Nacional Intercultural de la Amazonia, Pucallpa, Peru.ORCID 0000-0003-3376-590X
Víctor SánchezDepartment of Medicine, Neonatal Intensive Care Unit, Instituto Nacional de Salud del Niño, Lima, Peru.ORCID 0000-0002-0965-310X
Ruth AnayaSchool of Nursing, Universidad Nacional de San Cristóbal de Huamanga, Ayacucho, Peru.
Elaine FloresCentre for Global Public Health, Queen Mary University of London, London, UK.
Lorena RocaSchool of Nursing, Universidad Nacional de San Cristóbal de Huamanga, Ayacucho, Peru.
Víctor MamaniExecutive Office for Research Support and Specialized Teaching, Instituto Nacional de Salud del Niño, Lima, Peru.ORCID 0000-0002-5508-0883
Juan Rivera MedinaDepartment of Paediatrics, Faculty of Medicine, Universidad Nacional Mayor de San Marcos, Lima, Peru.ORCID 0000-0003-3562-7914
Pablo VelasquezDepartment of Medicine, Neonatal Intensive Care Unit, Instituto Nacional de Salud del Niño, Lima, Peru.
Carlos Del AguilaDepartment of Medicine, Endocrinology and Metabolism Unit, Instituto Nacional de Salud del Niño, Lima, Peru.ORCID 0000-0002-5345-5995
Andrew PrendergastBlizard Institute, Queen Mary University of London, London, UK.
Julio PalominoFaculty of Environmental Sciences, Universidad Nacional Santiago Antúnez de Mayolo, Huaraz, Peru.ORCID 0000-0002-4589-6774

Funding

Medical Research Council MR/S024654/1Wellcome TrustWellcome Trust 108065/Z/15/Z
6 · The paper itself

Abstract

backgroundPreventing infantile anaemia and ensuring optimal growth and development during early childhood, particularly in resource-constrained settings, represent an ongoing public health challenge. Current responses are aligned to treatment-based solutions, instead of determining the roles of its inter-related causes. This project aims to assess and understand the complex interplay of eco-bio-social-political factors that determine infantile anaemia to inform policy, research design and prevention practices.

methodsThis is a longitudinal birth cohort study including four components: (1) biological, will assess known blood markers of iron homeostasis and anaemia and stool microbiota to identify and genetically analyse the participants' flora; (2) ecological, will assess and map pollutants in air, water and soil and evaluate features of nutrition and perceived food security; (3) social, which will use different qualitative research methodologies to explore key stakeholders and informants' perceptions related to nutritional, environmental and anaemia topics, participant observations and a participatory approach and (4) a political analysis, to identify and assess the impact of policies, guidelines and programmes at all levels for infantile anaemia in the three regions. Finally, we will also explore the role of social determinants and demographic variables longitudinally for all study participants. This project aims to contribute to the evidence of the inter-related causal factors of infantile anaemia, addressing the complexity of influencing factors from diverse methodological angles. We will assess infantile anaemia in three regions of Peru, including newborns and their mothers as participants, from childbirth until their first year of age. ETHICS AND DISSEMINATION: Ethical approval was obtained from the Institutional Research Ethics Committee of the Instituto Nacional de Salud del Niño (Lima, Peru), CIEI-043-2019. An additional opinion has been granted by the Ethical Committee of Queen Mary University of London (London, UK). Dissemination across stakeholders is taking part as a continues part of the research process.

Indexed as

AnemiaChild, PreschoolCohort StudiesFemaleGrowth and DevelopmentHomeostasisHumansInfantInfant, NewbornIronLondonPeruIronanaemiahealth policymicrobiologyobstetricspaediatrics

Identifiers

PMID33986056
PMCPMC8126292

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.