Evidence map›Paper›PMID 33986023›Full record

ArticleClinical cancer research : an official journal of the American Association for Cancer Research2021

(Chemo)Radiotherapy-Immunotherapy Combinations: Time to Get Tailored?

Michele Mondini, Eric Deutsch

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Michele MondiniGustave Roussy, Université Paris-Saclay, INSERM U1030, Villejuif, France. eric.deutsch@gustaveroussy.fr michele.mondini@gustaveroussy.fr.
Eric DeutschGustave Roussy, Université Paris-Saclay, INSERM U1030, Villejuif, France. eric.deutsch@gustaveroussy.fr michele.mondini@gustaveroussy.fr.ORCID 0000-0002-8223-3697
Inserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemoradiotherapy is considered an immunogenic anticancer treatment. Data obtained during the course of chemoradiotherapy treatment of patients with cervical cancer show heterogeneous changes in the tumor immune landscape, highlighting the need for patient selection to rationally design successful combined immunotherapies. Blood-based biomarkers could be valuable to perform such stratification.

Indexed as

ImmunotherapyUterine Cervical NeoplasmsChemoradiotherapyDrug Therapy, CombinationFemaleHumansImmunologic FactorsImmunologic Factors

Identifiers

PMID33986023
OpenAlexW3163263327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.