Evidence map›Paper›PMID 33985970›Full record

ArticleGenes & development2021

piRNA-mediated gene regulation and adaptation to sex-specific transposon expression in

Peiwei Chen, Alexei A Kotov, Baira K Godneeva, Sergei S Bazylev, Ludmila V Olenina, Alexei A Aravin

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Frontiers in microbiology · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Paramutation-Like Behavior of Genic piRNA-Producing Loci inInternational journal of molecular sciences · 2025
    Article
  11. Article
  12. Review
  13. Escalation of genome defense capacity enables control of an expanding meiotic driver.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. New perspectives on the causes and consequences of male meiotic drive.Current opinion in genetics & development · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Peiwei Chen *California Institute of Technology, Division of Biology and Biological Engineering, Pasadena, California 91125, USA.ORCID 0000-0001-7160-6673
Alexei A Kotov *Institute of Molecular Genetics of National Research Center "Kurchatov Institute," Moscow 123182, Russia.
Baira K GodneevaCalifornia Institute of Technology, Division of Biology and Biological Engineering, Pasadena, California 91125, USA.
Sergei S BazylevInstitute of Molecular Genetics of National Research Center "Kurchatov Institute," Moscow 123182, Russia.
Ludmila V OleninaInstitute of Molecular Genetics of National Research Center "Kurchatov Institute," Moscow 123182, Russia.
Alexei A AravinCalifornia Institute of Technology, Division of Biology and Biological Engineering, Pasadena, California 91125, USA.
California Institute of Technology · USKurchatov Institute · RU

Funding

Molecular Mechanism of the piRNA BiogenesisR01GM097363 · NIGMS · CORNELL UNIVERSITY · PI ARAVIN, ALEXEI A. · 2011 to 2025
$4.0M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM097363
6 · The paper itself

Abstract

Small noncoding piRNAs act as sequence-specific guides to repress complementary targets in Metazoa. Prior studies in

Indexed as

Adaptation, PhysiologicalAnimalsDNA Transposable ElementsDrosophila melanogasterFemaleGene Expression Regulation, DevelopmentalGerm CellsMaleRNA, Small InterferingSex CharacteristicsSex FactorsDNA Transposable ElementsRNA, Small InterferingDrosophila mauritianaDrosophila melanogasterpiRNAsatellite DNAsexual dimorphismspermatogenesistransposable elementY chromosome

Identifiers

PMID33985970
PMCPMC8168559
OpenAlexW3160787014

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.