Trial reportRadiation oncology (London, England)2021
Deep-inspirational breath-hold (DIBH) technique in left-sided breast cancer: various aspects of clinical utility.
Trial report in Radiation oncology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical benefits of deep inspiration breath-hold in postoperative radiotherapy for right-sided breast cancer: a meta-analysis.BMC cancer · 2024Pooled it
- Trial
- Comparison Between Breath-Hold and the Inspiratory Phase of Free Breathing in Left Breast Cancer Radiotherapy: Target Volume Coverage and Organ Sparing.Asian Pacific journal of cancer prevention : APJCP · 2025Trial
- Evaluation of registration accuracy using short-arc cone-beam computed tomography for image-guided radiotherapy in breast cancer.Journal of applied clinical medical physics · 2026Article
- How reliable is deep inspiration breath hold at CT simulation? Clinical impact of surface-guided breathing training in breast cancer radiotherapy.Radiation oncology (London, England) · 2026Article
- Comparison of surface-guided radiotherapy-based deep inspiration breath hold and continuous positive airway pressure techniques in left-sided breast cancer: dosimetric and workflow analysis.Physical and engineering sciences in medicine · 2026Article
- Clinical evaluation using first-day assessment of patient suitability for successful performance of deep inspiration breath-hold for breast cancer radiotherapy.Radiation oncology (London, England) · 2026Article
- Dosimetric and radiobiological evaluations as well as technical aspects of left breast treatment employing DIBH with SGRT in radiotherapy with IMRT step and shoot, IMRT Dynamic MLC and VMAT.Journal of applied clinical medical physics · 2026Article
- Deformable image registration accuracy: impact of user-defined parameter selection on contour propagation for deep inspiration breath-hold and free breathing breast radiotherapy.BMC medical imaging · 2026Article
- Patient-specific breath-hold reproducibility in thoracic and abdominal radiotherapy: comparison of auditory and visual biofeedback.Japanese journal of radiology · 2026Article
- Structure visibility and online adaptation suitability of a new high-performance ring-gantry cone-beam computed tomography imaging system in thoracic radiotherapy.Physics and imaging in radiation oncology · 2026Article
- Comparative dosimetric analysis of deep inspiration breath-hold versus free breathing radiotherapy in lung cancer: special emphasis on cardiac and subcardiac structure protection.Technical innovations & patient support in radiation oncology · 2026Article
- Dosimetric comparison of DIBH and FB for left-sided breast cancer radiation therapy.Scientific reports · 2026Article
- Development of a model to guide the decision for radiotherapy in deep-inspiration breath-hold in patients with left-sided breast cancer.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- Feasibility and workflow efficiency of automated deep inspiration breath-hold for locoregional breast irradiation on a ring-gantry accelerator.Physics and imaging in radiation oncology · 2026Article
- Article
- Shortening breath-hold durations in breast radiotherapy: a novel time-control strategy for deep inspiration breath-hold VMAT.Radiation oncology (London, England) · 2025Article
- Postmastectomy Radiation Therapy: An ASTRO/ASCO/SSO Clinical Practice Guideline.Annals of surgical oncology · 2025Article
- Affordable realtime respiratory monitoring system for radiation oncology.Journal of applied clinical medical physics · 2025Article
- Robustness of Machine Learning Predictions for Determining Whether Deep Inspiration Breath-Hold Is Required in Breast Cancer Radiation Therapy.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundStudying the clinical utility of deep-inspirational breath-hold (DIBH) in left breast cancer radiotherapy (RT) was aimed at focusing on dosimetry and feasibility aspects.
methodsIn this prospective trial all enrolled patients went through planning CT in supine position under both DIBH and free breathing (FB); in whole breast irradiation (WBI) cases prone CT was also taken. In 3-dimensional conformal radiotherapy (3DCRT) plans heart, left anterior descending coronary artery (LAD), ipsilateral lung and contralateral breast doses were analyzed. The acceptance of DIBH technique as reported by the patients and the staff was analyzed; post-RT side-effects including radiation lung changes (visual scores and lung density measurements) were collected.
resultsAmong 130 enrolled patients 26 were not suitable for the technique while in 16, heart or LAD dose constraints were not met in the DIBH plans. Among 54 and 34 patients receiving WBI and postmastectomy/nodal RT, respectively with DIBH, mean heart dose (MHD) was reduced to < 50%, the heart V
conclusionsDIBH is an excellent heart sparing technique in breast RT, but about one-third of the patients do not benefit from that otherwise laborious procedure or benefit less than from an alternative method.
trial registrationretrospectively registered under ISRCTN14360721 (February 12, 2021).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.