ReviewScandinavian journal of trauma, resuscitation and emergency medicine2021
Rapid sequence induction: where did the consensus go?
Review in Scandinavian journal of trauma, resuscitation and emergency medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05364801 (Impact of Anxiety on the Decision-making Process of Anesthesiologists in the Choice of Drugs for Induction of General Anesthesia of Patients With Aspiration Risk Factors), which is not on this map. Cited by 19 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Impact of Anxiety on the Decision-making Process of Anesthesiologists in the Choice of Drugs for Induction of General Anesthesia of Patients With Aspiration Risk Factors
Who cites it
19 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Safer prehospital anaesthesia: updated guidelines from the Association of Anaesthetists.Anaesthesia · 2026Guideline
- Pooled it
- Review article: Effectiveness and risks of cricoid pressure during rapid sequence induction for endotracheal intubation in the emergency department: A systematic review.Emergency medicine Australasia : EMA · 2022Pooled it
- Comparative efficacy and safety of nalbuphine and hydromorphone in painless colonoscopy techniques: a randomized controlled trial.BMC anesthesiology · 2025Trial
- Intubating conditions during rapid sequence induction with either rocuronium or suxamethonium in elderly patients. A randomised study.Acta anaesthesiologica Scandinavica · 2025Trial
- Structured correction after difficult direct laryngoscopy during prehospital rapid sequence intubation: an eleven-year physician-staffed helicopter emergency medical service registry study.International journal of emergency medicine · 2026Article
- Airway Management in the ICU and Emergency Department in Resource-Limited Settings.Life (Basel, Switzerland) · 2026Review
- Prehospital Postintubation Hypotension and Survival in Severe Traumatic Brain Injury.JAMA network open · 2025Observational
- Comparison of Esketamine and Propofol for Prehospital Emergency Anaesthesia in Patients With Traumatic Brain Injury-A Retrospective Observational Study.Acta anaesthesiologica Scandinavica · 2025Observational
- The Effect of Drug Selection on Pediatric Rapid Sequence Induction Success: A Systematic Review and Meta-Analysis.Cureus · 2025Review
- SAFE anaesthesia for patients at risk of pulmonary aspiration: A nationwide survey.European journal of anaesthesiology and intensive care · 2025Article
- Maintenance of prehospital anaesthesia in trauma patients: inconsistencies and variability in practice.BJA open · 2025Article
- The process of rapid sequence intubation in the prehospital setting: A scoping review.The Southern African journal of critical care : the official journal of the Critical Care Society · 2025Review
- Combined use of dexmedetomidine and nalbuphine in laparoscopic radical gastrectomy for gastric cancer.World journal of gastrointestinal oncology · 2024Article
- Prehospital emergency anesthesia: A single-center retrospective analysis of guideline adherence and unexpected incidents.PloS one · 2024Article
- Protocol for a systematic review on effective patient positioning for rapid sequence intubation.BMJ open · 2022Article
- Etomidate Compared to Ketamine for Induction during Rapid Sequence Intubation: A Systematic Review and Meta-analysis.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022Review
- Recommendations from the Brazilian Society of Anesthesiology (SBA) for difficult airway management in adults.Brazilian journal of anesthesiology (Elsevier)Article
- Study protocol for the SECURE (RAFT-5) study: Service Evaluation of in-hospital Cross-speciality UK adult Rapid sequence intubation Events.Anaesthesia reportsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRapid Sequence Induction (RSI) was introduced to minimise the risk of aspiration of gastric contents during emergency tracheal intubation. It consisted of induction with the use of thiopentone and suxamethonium with the application of cricoid pressure. This narrative review describes how traditional RSI has been modified in the UK and elsewhere, aiming to deliver safe and effective emergency anaesthesia outside the operating room environment. Most of the key aspects of traditional RSI - training, technique, drugs and equipment have been challenged and often significantly changed since the procedure was first described. Alterations have been made to improve the safety and quality of the intervention while retaining the principles of rapidly securing a definitive airway and avoiding gastric aspiration. RSI is no longer achieved by an anaesthetist alone and can be delivered safely in a variety of settings, including in the pre-hospital environment.
conclusionThe conduct of RSI in current emergency practice is far removed from the original descriptions of the procedure. Despite this, the principles - rapid delivery of a definitive airway and avoiding aspiration, are still highly relevant and the indications for RSI remain relatively unchanged.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.