Evidence map›Paper›PMID 33985522›Full record

ArticleCost effectiveness and resource allocation : C/E2021

The impact of common chronic conditions on health-related quality of life: a general population survey in Iran using EQ-5D-5L.

Ali Akbari Sari, Fereshteh Karimi, Zahra Emrani, Hojjat Zeraati, Alireza Olyaeemanesh, Rajabali Daroudi

Open access · goldAbstract read
In one paragraph

Article in Cost effectiveness and resource allocation : C/E, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Associations of chronic obstructive pulmonary disease with life satisfaction and self-rated health: quantifying the subjective burden in a population-based study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ali Akbari SariDepartment of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Poursina Ave, 1417613191, Tehran, Iran.
Fereshteh KarimiDepartment of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Poursina Ave, 1417613191, Tehran, Iran.
Zahra EmraniDepartment of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Poursina Ave, 1417613191, Tehran, Iran.
Hojjat ZeraatiDepartment of Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran.
Alireza OlyaeemaneshNational Institute for Health Research & Health Equity Research Centre, Tehran University of Medical Sciences, Tehran, Iran.
Rajabali DaroudiDepartment of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, Poursina Ave, 1417613191, Tehran, Iran. rdaroudi@sina.tums.ac.ir.ORCID http://orcid.org/0000-0002-0487-4114
Tehran University of Medical Sciences · IR

Funding

Tehran University of Medical Sciences and Health Services 94-01-159-28771
6 · The paper itself

Abstract

backgroundDiseases have undeniable effects on Health-Related Quality of Life (HRQoL). Chronic diseases, in particular, limit the productive potentials and HRQoL of individuals. EQ-5D is a very popular generic instrument, which can be used to estimate HRQoL scores in any diseases. The current study investigates mean HRQoL scores in certain chronic diseases and examines the relationship between utility scores and chronic diseases in Iran.

methodThis cross-sectional study was carried out among the general adult population of Tehran. 3060 individuals were chosen by a stratified probability sampling method. The EQ-5D-5L questionnaire was applied. The utility scores were estimated using the Iranian crosswalk-based value set. The effect of chronic diseases on the HRQoL scores was derived by the Ordinary Least Squares (OLS) method. Data was analyzed using Stata version 13 software.

resultsThe mean ± standard deviation utility and EQ-VAS scores were 0.85 ± 0.14 and 76.73 ± 16.55 in the participants without any chronic conditions. The scores were 0.69 ± 0.17 and 61.14 ± 20.61 in the participants with chronic conditions. The highest and lowest mean utility scores were related to thyroid disease (0.70) and Stroke (0.54), respectively. Common chronic conditions had significant negative effects on the HRQoL scores. Stroke (0.204) and cancer (0.177) caused the most reduction in the EQ-5D-5L utility scores. Lumbar disc hernia, digestive diseases, osteoarthritis, breathing problems, and anxiety/nerves cause 0.133, 0.109, 0.108, 0.087, and 0.078 reductions, respectively, in the EQ-5D-5L utility scores.

conclusionThis study provides insight into some common chronic conditions and their effects on the HRQoL. Policymakers and planners should pay attention to the effects of chronic conditions especially high prevalence one. They should adopt effective interventions to control this issue and increase health. The results of this study can also be beneficial in economic evaluation studies.

Indexed as

Chronic diseaseEconomic evaluationEQ-5DHealth-related quality of lifeIran

Identifiers

PMID33985522
PMCPMC8117596
OpenAlexW3136221692

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.