Evidence map›Paper›PMID 33985509›Full record

Trial reportCardiovascular diabetology2021

Effects of hybrid comprehensive telerehabilitation on cardiopulmonary capacity in heart failure patients depending on diabetes mellitus: subanalysis of the TELEREH-HF randomized clinical trial.

Renata Główczyńska, Ewa Piotrowicz, Dominika Szalewska, Ryszard Piotrowicz, Ilona Kowalik, Michael J Pencina, Wojciech Zaręba, Maciej Banach, Piotr Orzechowski, Sławomir Pluta and 3 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Cardiovascular diabetology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02523560 (Applying Telemedicine Technologies in a Novel Model of Organizing and Implementing Comprehensive Cardiac Rehabilitation in Heart Failure Patients - TELEREH-HF), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02523560 nacompletednot on this map

Applying Telemedicine Technologies in a Novel Model of Organizing and Implementing Comprehensive Cardiac Rehabilitation in Heart Failure Patients - TELEREH-HF

TypeinterventionalSponsorNational Institute of Cardiology, Warsaw, PolandRan2015 to 2018Enrolled850ConditionsChronic Heart FailureArmshome-based telerehabilitation
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

  1. Exercise-based cardiac rehabilitation for adults with heart failure.The Cochrane database of systematic reviews · 2024
    Pooled it
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  7. Review
  8. Effects of cardiac rehabilitation on cardiopulmonary test parameters in heart failure: A real world experience.International journal of cardiology. Cardiovascular risk and prevention · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Renata Główczyńska1st Chair and Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Ewa PiotrowiczTelecardiology Center, National Institute of Cardiology, Alpejska Str. 42, 04-828, Warsaw, Poland. epiotrowicz@ikard.pl.
Dominika SzalewskaClinic of Rehabilitation Medicine, Faculty of Health Sciences, Medical University of Gdańsk, Gdańsk, Poland.
Ryszard PiotrowiczNational Institute of Cardiology, Warsaw, Poland.
Ilona KowalikNational Institute of Cardiology, Warsaw, Poland.
Michael J PencinaDuke University School of Medicine, Durham, NC, USA.
Wojciech ZarębaUniversity of Rochester Medical Center, Rochester, NY, USA.
Maciej BanachDepartment of Hypertension, Medical University of Łódź, Lodz, Poland.
Piotr OrzechowskiTelecardiology Center, National Institute of Cardiology, Alpejska Str. 42, 04-828, Warsaw, Poland.
Sławomir PlutaDepartment of Cardiology, Congenital Heart Diseases and Electrotherapy, Silesian Center for Heart Diseases, Silesian Medical University, Zabrze, Poland.
Robert IrzmańskiDepartment of Internal Medicine and Cardiac Rehabilitation, Medical University of Łódź, Lodz, Poland.
Zbigniew KalarusDepartment of Cardiology, Congenital Heart Diseases and Electrotherapy, Silesian Center for Heart Diseases, Silesian Medical University, Zabrze, Poland.
Grzegorz Opolski1st Chair and Department of Cardiology, Medical University of Warsaw, Warsaw, Poland.
Institute of Cardiology · PLMedical University of Lodz · PLMedical University of Warsaw · PLSilesian Center for Heart Disease · PLDuke University · USGdańsk Medical University · PLUniversity of Rochester Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundType 2 diabetes mellitus (DM) is one of the most common comorbidities among patients with heart failure (HF) with reduced ejection fraction (HFrEF). There are limited data regarding efficacy of hybrid comprehensive telerehabilitation (HCTR) on cardiopulmonary exercise capacity in patients with HFrEF with versus those without diabetes.

aimThe aim of the present study was to analyze effects of 9-week HCTR in comparison to usual care on parameters of cardiopulmonary exercise capacity in HF patients according to history of DM.

methodsClinically stable HF patients with left ventricular ejection fraction [LVEF] < 40% after a hospitalization due to worsening HF within past 6 months were enrolled in the TELEREH-HF (The TELEREHabilitation in Heart Failure Patients) trial and randomized to the HCTR or usual care (UC). Cardiopulmonary exercise tests (CPET) were performed on treadmill with an incremental workload according to the ramp protocol.

resultsCPET was performed in 385 patients assigned to HCTR group: 129 (33.5%) had DM (HCTR-DM group) and 256 patients (66.5%) did not have DM (HCTR-nonDM group). Among 397 patients assigned to UC group who had CPET: 137 (34.5%) had DM (UC-DM group) and 260 patients (65.5%) did not have DM (UC-nonDM group). Among DM patients, differences in cardiopulmonary parameters from baseline to 9 weeks remained similar among HCTR and UC patients. In contrast, among patients without DM, HCTR was associated with greater 9-week changes than UC in exercise time, which resulted in a statistically significant interaction between patients with and without DM: difference in changes in exercise time between HCTR versus UC was 12.0 s [95% CI - 15.1, 39.1 s] in DM and 43.1 s [95% CI 24.0, 63.0 s] in non-DM, interaction p-value = 0.016. Furthermore, statistically significant differences in the effect of HCTR versus UC between DM and non-DM were observed in ventilation at rest: - 0.34 l/min [95% CI - 1.60, 0.91 l/min] in DM and 0.83 l/min [95% CI - 0.06, 1.73 l/min] in non-DM, interaction p value = 0.0496 and in VE/VCO

conclusionsThe benefits of hybrid comprehensive telerehabilitation versus usual care on the improvement of physical performance, ventilatory profile and gas exchange parameters were more pronounced in patients with HFrEF without DM as compared to patients with DM.

trial registrationClinicalTrials.gov Identifier: NCT02523560. Registered 3rd August 2015. https://clinicaltrials.gov/ct2/show/NCT02523560?term=NCT02523560&draw=2&rank=1 . Other Study ID Numbers: STRATEGME1/233547/13/NCBR/2015.

Indexed as

Cardiac RehabilitationExercise TherapyExercise ToleranceStroke VolumeTelerehabilitationVentricular Function, LeftAgedDiabetes Mellitus, Type 2Exercise TestFemaleHeart FailureHumansLungMaleMiddle AgedPolandDiabetes mellitusExercise trainingHeart failureHybrid rehabilitationTelerehabilitation

Identifiers

PMID33985509
PMCPMC8120915
OpenAlexW3160939433

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.