Evidence map›Paper›PMID 33985461›Full record

ArticleBMC public health2021

Lifecourse socioeconomic changes and late-life cognition in a cohort of U.S.-born and U.S. immigrants: findings from the KHANDLE study.

Rachel L Peterson, Kristen M George, Paola Gilsanz, Elizabeth Rose Mayeda, M Maria Glymour, Oanh L Meyer, Dan M Mungas, Charles DeCarli, Rachel A Whitmer

Open access · goldAbstract read
In one paragraph

Article in BMC public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Lifecourse socioeconomic status and subjective cognitive decline among diverse older adults.The journals of gerontology. Series B, Psychological sciences and social sciences · 2026
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  13. Race, community disadvantage, and cognitive decline: Findings from KHANDLE and STAR.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  14. Article
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  17. Effects of early-life environment and adulthood SES on cognitive change in a multiethnic cohort.Journal of the International Neuropsychological Society : JINS · 2023
    Article
  18. Global rural health disparities in Alzheimer's disease and related dementias: State of the science.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Rachel L PetersonBiomedical Sciences 1C, University of California Davis School of Medicine, One Shields Ave., Davis, CA, 95616, USA. rpeterson@ucdavis.edu.ORCID 0000-0001-6818-7009
Kristen M GeorgeBiomedical Sciences 1C, University of California Davis School of Medicine, One Shields Ave., Davis, CA, 95616, USA.
Paola GilsanzKaiser Permanente Northern California Division of Research, Oakland, CA, USA.
Elizabeth Rose MayedaUniversity of California Los Angeles School of Public Health, Los Angeles, CA, USA.
M Maria GlymourUniversity of California San Francisco School of Medicine, San Francisco, CA, USA.
Oanh L MeyerBiomedical Sciences 1C, University of California Davis School of Medicine, One Shields Ave., Davis, CA, 95616, USA.
Dan M MungasBiomedical Sciences 1C, University of California Davis School of Medicine, One Shields Ave., Davis, CA, 95616, USA.
Charles DeCarliBiomedical Sciences 1C, University of California Davis School of Medicine, One Shields Ave., Davis, CA, 95616, USA.
Rachel A WhitmerBiomedical Sciences 1C, University of California Davis School of Medicine, One Shields Ave., Davis, CA, 95616, USA.
University of California, Davis · USKaiser Permanente · USUniversity of California, Los Angeles · USUniversity of California, San Francisco · US

Funding

Lifecourse health, cerebral pathology and ethnic disparities in dementiaRF1AG052132 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DECARLI, CHARLES, GLYMOUR, MEDELLENA MARIA · 2016 to 2016
$13.1M
Scientific and Technical CoreP2CHD041022 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HIRAM BELTRAN-SANCHEZ · 2016 to 2026
$6.9M
Neuroscience of Cognitive AgingT32AG050061 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DECARLI, CHARLES · 2016 to 2020
$869k
NIA NIH HHS 7RF1AG052132-02NIA NIH HHS RF1 AG052132NIA NIH HHS T32 AG050061NICHD NIH HHS P2C HD041022
6 · The paper itself

Abstract

backgroundLow socioeconomic status (SES) in early and late life has been associated with lower late-life cognition. Less is known about how changes in SES from childhood to late life are associated with late-life cognition, especially among diverse populations of older adults.

methodsIn a multi-ethnic sample (n = 1353) of older adults, we used linear regression to test associations of change in comprehensive measures of SES (financial, cultural, and social domains) from childhood to late life with semantic memory, episodic memory, and executive function. We tested whether the association between SES trajectory and late-life cognition differed by populations who resided in the U.S. during childhood or immigrated to the U.S. as adults.

resultsParticipants with low childhood/high late-life financial capital had better semantic memory (β = 0.18; 95% CI: 0.04, 0.32) versus those with low financial capital in both childhood and late life, regardless of childhood residence. We observed a significant interaction in the association of verbal episodic memory and cultural capital by childhood residence (p = 0.08). Participants with a foreign childhood residence had higher verbal episodic memory if they had low childhood/high late-life cultural capital (β = 0.32; 95% CI: 0.01, 0.63), but lower verbal episodic memory if they had high childhood/low late-life cultural capital (β = - 0.40; 95% CI: - 0.94, 0.13). Having high lifecourse social capital was associated with better verbal episodic memory scores among those with a U.S. childhood (β = 0.34; 95% CI: 0.14, 0.55), but lower verbal episodic memory among those with a foreign childhood (β = - 0.10; 95% CI: - 0.51, 0.31).

conclusionsHigh financial and cultural capital in late life is associated with better cognition, regardless of early childhood SES or childhood residence.

Indexed as

CognitionEmigrants and ImmigrantsAgedChild, PreschoolCohort StudiesExecutive FunctionHumansSocial ClassSocioeconomic FactorsCognitive agingImmigrantsLifecourseSocioeconomic status

Identifiers

PMID33985461
PMCPMC8120825
OpenAlexW3160226251

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.