Evidence map›Paper›PMID 33984891›Full record

ArticleTurkish journal of medical sciences2021

Effects of regular whey protein consumption on rat thyroid functions

Gökhan Akkurt, Bahar Kartal, Mustafa Alimoğulları, Sevil Çaylı, Ebru Alimoğulları

Open access · greenAbstract read
In one paragraph

Article in Turkish journal of medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Gökhan AkkurtDepartment of Surgical Oncology, Ankara City Hospital, Ankara, TurkeyORCID 0000-0002-0908-4226
Bahar KartalDepartment of Histology Embryology, Medical College, Ankara Yıldırım Beyazıt University, Ankara, TurkeyORCID 0000-0001-9558-4122
Mustafa AlimoğullarıDepartment of General Surgery, Yenimahalle Education and Research Hospital, Ankara, TurkeyORCID 0000-0003-0844-301X
Sevil ÇaylıDepartment of Histology Embryology, Medical College, Ankara Yıldırım Beyazıt University, Ankara, TurkeyORCID 0000-0003-2465-5389
Ebru AlimoğullarıDepartment of Histology Embryology, Medical College, Ankara Yıldırım Beyazıt University, Ankara, TurkeyORCID 0000-0002-9557-3631
Ankara Yıldırım Beyazıt University · TRMemorial Ankara Hospital · TRYenişehir Hospital · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/aim: We aimed to investigate whether there was a significant difference in TSH, T3, T4 values and histopathologically evaluated thyroid tissues between rats that received ısole hydrolyzed whey protein (IHWP) at different doses regularly and rats fed with only standard feed. Material & methods: Total 24 rats were randomly divided into three groups with 8 rats in each group. First group were fed with standard feed for 12 weeks. Second group were given standard feed + daily 0.3 g/kg IHWP and rats in the third group standard feed + 0.5 g/kg IHWP for 12 weeks. Blood samples were collected from all rats before and after IHWP administration. All rats were then sacrificed, and thyroid tissues were histopathologically examined. Results: Interfollicular connective tissue areas and TSH (0.35–4.90 μIU/L) were higher in the control group compared to 3 cc IHWP and 5 cc IHWP groups, while thyroid hormone T4 (0.7–1.48 ng/dL), and thyroid hormone synthesis parameters including intrafollicular colloid amount, follicular diameter, and epithelial height were significantly higher in 3 cc and 5 cc IHWP groups compared to the control. Conclusion: We think that regular daily use of IHWP may increase the synthesis of thyroid hormone due to its high amino acid content.

Indexed as

HyperthyroidismHypothyroidismAnimalsRatsThyroid GlandThyroid HormonesThyrotropinThyroxineWheyWhey ProteinsThyroid HormonesThyrotropinThyroxineWhey ProteinshyperthyroidismhypothyroidismIsole hydrolyzed whey proteinthyroid function

Identifiers

PMID33984891
PMCPMC8569766
OpenAlexW3160451041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.