Evidence map›Paper›PMID 33984712›Full record

ReviewCurrent opinion in plant biology2021

Nanoparticles for protein delivery in planta.

Jeffrey W Wang, Francis J Cunningham, Natalie S Goh, Navid N Boozarpour, Matthew Pham, Markita P Landry

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current opinion in plant biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 60 citations in OpenAlex.

  1. Review
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  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Application of Nanotechnology in Plant Genetic Engineering.International journal of molecular sciences · 2023
    Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Nanomaterials coupled with microRNAs for alleviating plant stress: a new opening towards sustainable agriculture.Physiology and molecular biology of plants : an international journal of functional plant biology · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jeffrey W WangDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, 94720, USA.
Francis J CunninghamDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, 94720, USA.
Natalie S GohDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, 94720, USA.
Navid N BoozarpourDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, 94720, USA.
Matthew PhamDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, 94720, USA.
Markita P LandryDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA, 94720, USA; Innovative Genomics Institute (IGI), Berkeley, CA, 94720, USA; California Institute for Quantitative Biosciences, QB3, University of California, Berkeley, CA, 94720, USA; Chan-Zuckerberg Biohub, San Francisco, CA, 94158, USA. Electronic address: landry@berkeley.edu.
University of California, Berkeley · USQB3 · US

Funding

Single-Molecule Imaging of Biological Trauma:Cytokine-Based Intracellular CommunicationR35GM128922 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI LANDRY, MARKITA · 2019 to 2023
$2.0M
NIGMS NIH HHS R35 GM128922
6 · The paper itself

Abstract

Delivery of proteins into walled plant cells remains a challenge with few tractable solutions. Recent advances in biomacromolecule delivery using nanotechnology may evince methods to be exploited for protein delivery. While protein delivery remains no small feat, even in mammalian systems, the ability for nanoparticles to penetrate the cell wall and be decorated with a plethora of functional moieties makes them ideal protein vehicles in plants. As advances in protein biotechnology accelerate, so does the need for commensurate delivery systems. However, the road to nanoparticle-mediated protein delivery is fraught with challenges in regard to cell wall penetration, intracellular delivery, endosomal escape, and nanoparticle chemistry and design. The dearth of literature surrounding protein delivery in walled plant cells hints at the challenge of this problem but also indicates vast opportunity for innovations in plant-tailored nanotechnology.

Indexed as

NanoparticlesAnimalsEndosomesNanotechnologyPlantsEngineered nanomaterialsIn planta deliveryProtein delivery

Identifiers

PMID33984712
PMCPMC10461801
OpenAlexW3161135302

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.