Evidence map›Paper›PMID 33984276›Full record

ArticleCell host & microbe2021

Hair of the mouse: A skin bacteria "cocktail" gets follicles back on their feet.

Jeanmarie R Gonzalez, Geil R Merana, Tiffany C Scharschmidt

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell host & microbe, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. The skin microbiome in dermatologic disease.Journal of the American Academy of Dermatology · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Jeanmarie R GonzalezBiomedical Sciences Program, University of California, San Francisco, CA 94143, USA; Department of Dermatology, University of California, San Francisco, CA 94143, USA.
Geil R MeranaBiomedical Sciences Program, University of California, San Francisco, CA 94143, USA; Department of Dermatology, University of California, San Francisco, CA 94143, USA.
Tiffany C ScharschmidtDepartment of Dermatology, University of California, San Francisco, CA 94143, USA. Electronic address: tiffany.scharschmidt@ucsf.edu.

Funding

MOLECULAR AND CELLULAR IMMUNOLOGYT32AI007334 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CYSTER, JASON G · 1988 to 2023
$11.0M
Microbial Pathogenesis and Host DefenseT32AI060537 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joanne N. Engel · 2004 to 2026
$6.5M
NIAID NIH HHS T32 AI007334NIAID NIH HHS T32 AI060537
6 · The paper itself

Abstract

Microbes can boost cutaneous immune defense and skin reparative capacity. However, mechanistic understanding, especially of the latter, remains sparse. In this issue of Cell Host & Microbe, Wang et al. (2021) shed light on this, demonstrating that bacteria contribute to hair follicle neogenesis after skin wounding via keratinocyte-intrinsic IL-1R1 signaling.

Indexed as

Hair FollicleSkinAnimalsBacteriaMiceRegenerationSignal Transduction

Identifiers

PMID33984276

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.