ArticleTrends in psychiatry and psychotherapy2022
Adverse childhood experiences in patients with psoriasis.
Article in Trends in psychiatry and psychotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed, 8 citations in OpenAlex.
- The role of psychological stress in the pathogenesis of psoriasis.Frontiers in medicine · 2025Review
- Using Microbiome-Based Approaches to Deprogram Chronic Disorders and Extend the Healthspan following Adverse Childhood Experiences.Microorganisms · 2022Review
- Adverse Childhood Experiences and Pediatric Dermatology: Implications for Care, Equity, and Research.Pediatric dermatologyReview
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAdverse childhood experiences (ACEs) have been linked to occurrence of autoimmune diseases in adults, including psoriasis.
objectivesTo study the prevalence of ACEs in psoriasis patients, comparing them with a sample from the general population.
methodsThree hundred and eighteen individuals were included (104 psoriasis patients and 214 controls). Patients and controls answered questions on an ACE study questionnaire about experiences of childhood abuse, negligence, domestic violence, and household dysfunction. Questionnaire scores range from zero (best result) to 8 (worst scenario). Psoriasis patients' charts were reviewed for epidemiological, clinical, and treatment data. A Psoriasis Area Severity Index (PASI) was calculated from measurements taken when the questionnaire was administered.
resultsPsoriasis patients reported a median of 4 ACEs (interquartile range [IQR] = 3-5) while controls had a median of 3 (IQR = 2-4) with p < 0.0001. The number of ACEs was not associated with PASI, age of disease onset, or presence of associated arthritis (all p > 0.5). Female psoriasis patients had more ACEs than males (p = 0.04).
conclusionPatients with psoriasis have more ACEs than controls and ACEs were more common in female patients.
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Registered trials
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