ArticlePloS one2021
Does blood type affect the COVID-19 infection pattern?
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 43 citations in OpenAlex.
- Blood Group Type and COVID-19 Severity at Tertiary Care Centre, Nepal: An Observational Study.JNMA; journal of the Nepal Medical Association · 2025Observational
- Examination of iatrogenic FDG accumulation after COVID-19 vaccination.Annals of nuclear medicine · 2024Article
- Article
- A Pilot Study on COVID-19 Positive Subjects: An Excerpt of Post-Infection-Pro-Diabetic Disposition & Related Consequences in Correlation to Hepato-Pancreatic Bio-Markers, Pro-Inflammatory Cytokines and Other Risk Factors.Indian journal of clinical biochemistry : IJCB · 2023Article
- ABO blood group as a determinant of COVID-19 and Long COVID: An observational, longitudinal, large study.PloS one · 2023Observational
- ASSOCIATION OF BLOOD TYPE AND MORTALITY OF COVID-19: A HOSPITAL-BASED STUDY IN NATIONAL REFERRAL HOSPITAL, INDONESIA.African journal of infectious diseases · 2023Article
- Combined use of lactoferrin and vitamin D as a preventive and therapeutic supplement for SARS-CoV-2 infection: Current evidence.World journal of clinical cases · 2022Review
- Association between ABO blood groups and the risk of infection with SARS-CoV-2 in Iraq.The Journal of international medical research · 2022Article
- The Importance of Behavioral and Native Factors on COVID-19 Infection and Severity: Insights from a Preliminary Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2022Article
- Lactoferrin Inhibition of the Complex Formation between ACE2 Receptor and SARS CoV-2 Recognition Binding Domain.International journal of molecular sciences · 2022Article
- Association of Covid-19 with blood type A in relation to blood sugar, urea, and blood test (D-dimer and ferritin) in patients from Al-Najaf.Journal of medicine and life · 2022Article
- Confirmed circulation of SARS-CoV-2 in Irish blood donors prior to first national notification of infection.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2022Article
- Role of ABO Blood Groups in Susceptibility and Severity of COVID-19 in the Georgian Population.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2022Article
- Effects of ABO blood groups and RH-factor on COVID-19 transmission, course and outcome: A review.Frontiers in medicine · 2022Review
- Associations Between Symptoms, Donor Characteristics and IgG Antibody Response in 2082 COVID-19 Convalescent Plasma Donors.Frontiers in immunology · 2022Observational
- Relationship Between ABO Blood Types and Coronavirus Disease 2019 Severity.Sisli Etfal Hastanesi tip bulteni · 2022Article
- Country-level factors dynamics and ABO/Rh blood groups contribution to COVID-19 mortality.Scientific reports · 2021Article
- Article
- Modelling suggests ABO histo-incompatibility may substantially reduce SARS-CoV-2 transmission.Epidemics · 2021Article
- In Planta Production of the Receptor-Binding Domain From SARS-CoV-2 With Human Blood Group A Glycan Structures.Frontiers in chemistry · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Among the many aspects that characterize the COVID-19 pandemic, two seem particularly challenging to understand: i) the great geographical differences in the degree of virus contagiousness and lethality that were found in the different phases of the epidemic progression, and, ii) the potential role of the infected people's blood type in both the virus infectivity and the progression of the disease. A recent hypothesis could shed some light on both aspects. Specifically, it has been proposed that, in the subject-to-subject transfer, SARS-CoV-2 conserves on its capsid the erythrocytes' antigens of the source subject. Thus these conserved antigens can potentially cause an immune reaction in a receiving subject that has previously acquired specific antibodies for the source subject antigens. This hypothesis implies a blood type-dependent infection rate. The strong geographical dependence of the blood type distribution could be, therefore, one of the factors at the origin of the observed heterogeneity in the epidemics spread. Here, we present an epidemiological deterministic model where the infection rules based on blood types are taken into account, and we compare our model outcomes with the exiting worldwide infection progression data. We found an overall good agreement, which strengthens the hypothesis that blood types do play a role in the COVID-19 infection.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.