ArticlePLoS neglected tropical diseases2021
Rickettsial infections: A blind spot in our view of neglected tropical diseases.
Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- The diagnostic accuracy of point-of-care nucleic acid-based isothermal amplification assays for scrub typhus: a systematic review and meta-analysis.Frontiers in microbiology · 2024Pooled it
- A systematic review of neglected tropical diseases (NTDs) in Myanmar.PLoS neglected tropical diseases · 2023Pooled it
- Mapping the global distribution of spotted fever group rickettsiae: a systematic review with modelling analysis.The Lancet. Digital health · 2023Pooled it
- School-based one health education shapes young minds and households to prevent zoonoses: A comparison of four teaching strategies.One health (Amsterdam, Netherlands) · 2026Article
- Early diagnostic performance of real-time PCR versus serology for murine typhus and Q fever in a public health setting.BMC infectious diseases · 2026Article
- Sand fly endosymbionts in Kenya: Rickettsia and Wolbachia associations with Leishmania and detection of Rickettsia africae.Parasites & vectors · 2026Article
- Assessment of the Pathogenicity ofPathogens (Basel, Switzerland) · 2026Article
- Antibodies to Tick Salivary Antigens AV422 and Calreticulin in Patients With Spotted Fever Group Rickettsioses and Other Febrile Illnesses in Northern Tanzania.The Journal of infectious diseases · 2026Article
- Bridging historical antigenic profiling and whole-genome taxonomy inScientific reviews · 2026Review
- Article
- Preliminary molecular detection and characterization ofOne health (Amsterdam, Netherlands) · 2025Article
- Epidemiology and Clinical Characteristics of Human Rickettsial Infections Detected in Nigeria: Discovery of a Significant Contributor to Acute Febrile Illness.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- Survey of Fleas and Ticks for Rickettsia rickettsii and Rickettsia typhi in the El Paso Community and Other Areas in Texas, New Mexico, and Ciudad Juarez, Mexico.The American journal of tropical medicine and hygiene · 2025Article
- Rickettsioses Seropositivity in Malaysia: A Six-Year Trend, 2016-2021.Tropical medicine and infectious disease · 2025Article
- Clinical Manifestations, Risk Factors, and Disease Burden of Rickettsiosis, Cambodia, 2007-2020.Emerging infectious diseases · 2025Review
- Revisiting What Constitutes a Neglected Tropical Disease?PLoS neglected tropical diseases · 2025Article
- Leptospirosis, melioidosis, and rickettsioses in the vicious circle of neglect.PLoS neglected tropical diseases · 2025Review
- Rickettsiosis Infections in Sarawak: Epidemiological Insights and Public Health Strategies.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2025Review
- Investigation of potentially zoonoticScience in One Health · 2025Article
- Molecular identification of tick-borne Rickettsia, Anaplasma, Ehrlichia, Babesia, and Colpodella in confiscated Malayan pangolins.PLoS neglected tropical diseases · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 6 countries.
Funding
Abstract
Rickettsial diseases are a group of vector-borne bacterial infections that cause acute febrile illness with potentially severe or fatal complications. These vector-borne diseases are prevalent in tropical and subtropical regions worldwide and disproportionately affect poorer communities but are scientifically underrecognized. Despite this, they are not included in the World Health Organization's list of neglected tropical diseases nor were they mentioned in Peter Hotez's recent reflections on "What constitutes a neglected tropical disease?" in PLOS Neglected Tropical Diseases [1]. Here we present the case that rickettsial infections, as an overlooked cause of morbidity, mortality, and economic losses in marginalized populations, should be recognized as neglected tropical diseases. We describe how this oversight is the result of a number of factors and how it negatively impacts patient outcomes. We then propose measures to address the neglect of rickettsial infections in both scientific research and public health interventions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.