Evidence map›Paper›PMID 33983848›Full record

ArticleJournal of adolescent and young adult oncology2022

Barriers to Pediatric Oncologist Enrollment of Adolescents and Young Adults on a Cross-Network National Clinical Trials Network Supportive Care Cancer Clinical Trial.

Nupur Mittal, Anne-Marie Langevin, Wade Kyono, David S Dickens, Allison Grimes, John M Salsman, Brad H Pollock, Michael Roth

Abstract read
In one paragraph

Article in Journal of adolescent and young adult oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Access to Care for Adolescents and Young Adults With Cancer in the United States: State of the Literature.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Challenges of Systemic Therapy Investigations for Bone Sarcomas.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nupur MittalDepartment of Pediatrics, Rush University Children's Hospital, Chicago, Illinois, USA.ORCID 0000-0002-9622-7757
Anne-Marie LangevinDepartment of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Wade KyonoDepartment of Pediatrics, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii, USA.
David S DickensDivision of Hematology, Oncology and Bone Marrow Transplantation, Department of Pediatrics, Holden Comprehensive Cancer, University of Iowa, Iowa City, Iowa, USA.
Allison GrimesDepartment of Pediatrics, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
John M SalsmanDepartment of Social Sciences and Health Policy, Wake Forest Baptist Comprehensive Cancer Center, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Brad H PollockDepartment of Public Health Sciences, Comprehensive Cancer Center, School of Medicine, University of California, Davis, Davis, California, USA.
Michael RothDepartment of Pediatrics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Towards a preventive cancer vaccine for children with constitutional mismatch repair deficiencyUG1CA189955 · NCI · PUBLIC HEALTH INSTITUTE · PI BRAD H POLLOCK, Michael E. Roth · 2014 to 2026
$62.5M
The Hawaii NCORPUG1CA189804 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI Jared Acoba, Jeffrey Lee Berenberg · 2014 to 2026
$15.7M
NCI NIH HHS P30 CA016672NCI NIH HHS U10 CA180886NCI NIH HHS UG1 CA189804NCI NIH HHS UG1 CA189955
6 · The paper itself

Abstract

Few studies have explored interventions to improve adolescent and young adult (AYA) cancer care delivery. While many AYAs receive cancer care at NCI Community Oncology Research Program (NCORP) sites, few enroll on clinical trials. Barriers and facilitators to pediatric oncologist activation of and enrollment on an AYA cross-network National Clinical Trials Network (NCTN) supportive care trial were assessed using a survey that was administered to 162 stakeholders representing all 47 children's oncology group (COG) institutions affiliated to an NCORP. Fifty-eight stakeholders participated representing 62% of all sites surveyed. Approximately half of participants (45%) were unaware of the trial. Seven sites had the study open and one enrolled a patient. Reasons for not opening and enrolling on the trial included limited research staff and resources, low anticipated accrual, and lower prioritization of the trial. Enrollment facilitators included having a local "AYA champion," improving communication between pediatric and medical oncology, and having site education on available AYA trials. Interventions focused on increasing site and provider awareness of AYA trials and decreasing local barriers to AYA enrollment are needed.

Indexed as

NeoplasmsOncologistsPatient SelectionAdolescentClinical Trials as TopicHumansYoung Adultadolescent and young adultcancer clinical trialdisparityenrollmentNCORPoncofertility

Identifiers

PMID33983848
PMCPMC8864435

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.