ArticlePediatric radiology2021
Acoustic radiation force impulse imaging: normal values of spleen stiffness in healthy children.
Article in Pediatric radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Spleen and liver shear wave elastography for assessment of portal hypertension in children with biliary atresia.Scientific reports · 2026Article
- Splenic shear wave elastography beyond portal hypertension: a narrative review of non-portal applications.Journal of ultrasonography · 2026Review
- Ultrasound innovations in abdominal radiology: techniques and clinical applications in pediatric imaging.Abdominal radiology (New York) · 2025Review
- Differentiating Benign from Malignant Causes of Splenomegaly: Is Acoustic Radiation Force Impulse Elastography Helpful?Diseases (Basel, Switzerland) · 2024Article
- Spleen stiffness measurement as a non-invasive assessment in patients with portal hypertension.eGastroenterology · 2024Review
- Acoustic Radiation Force Impulse (ARFI) Elastography of Focal Splenic Lesions: Feasibility and Diagnostic Potential.Cancers · 2023Article
- Ultrasound Elastography in Children.Children (Basel, Switzerland) · 2023Review
- Ultrasound elastography in children - nice to have for scientific studies or arrived in clinical routine?Molecular and cellular pediatrics · 2022Review
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcoustic radiation force impulse (ARFI) imaging is a noninvasive ultrasound elastography technique for evaluating tissue stiffness. The association of liver and spleen stiffness provides additional information in the assessment of portal hypertension. The technique and normal values of spleen stiffness by point shear wave elastography (p-SWE) in pediatrics have not been well documented.
objectiveOur aim is to describe the feasibility and normal ARFI elastography values in the spleen for healthy children and to compare measurements in two different probe positions (the axial and sagittal planes). MATERIALS AND
methodsSpleen p-SWE using ARFI values were measured with a 6C1 probe in 102 healthy children (age range: 8 weeks to 17 years) divided into four age groups. An average of nine (standard deviation: two) spleen stiffness measurements were taken during free breathing in each plane (axial and sagittal). The impact of age and measurement plane in the spleen was analyzed using multivariate models.
resultsThere was no significant difference in spleen stiffness values taken at different ages, with an average of the medians of 2.43±0.31 m/s. There was no significant difference based on probe orientation: sagittal plane (median: 2.46±0.29 m/s) and axial plane (median: 2.43±0.32 m/s) with Student's t-test P=0.18. The mean depth of measurement varied between 2.3 cm and 3.7 cm, according to age.
conclusionNormal spleen stiffness values using ARFI imaging in children do not vary with age and correspond to a median of 2.43 m/s. No significant difference was found when using different probe positions.
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