Evidence map›Paper›PMID 33982835›Full record

ArticleJournal of cellular and molecular medicine2021

Prostaglandin E

Jing Cui, Kai Shan, Qin Yang, Yumin Qi, Hongyan Qu, Jiaqi Li, Rong Wang, Lingling Jia, Wei Chen, Ninghan Feng and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  13. Article
  14. Regulatory Roles for SIRT1 in Aging and Immunosenescence.Results and problems in cell differentiation · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Jing CuiWuxi School of Medicine, Jiangnan University, Wuxi, China.ORCID 0000-0002-8157-2910
Kai ShanWuxi School of Medicine, Jiangnan University, Wuxi, China.ORCID 0000-0002-6799-3946
Qin YangWuxi School of Medicine, Jiangnan University, Wuxi, China.
Yumin QiWuxi School of Medicine, Jiangnan University, Wuxi, China.
Hongyan QuWuxi School of Medicine, Jiangnan University, Wuxi, China.
Jiaqi LiWuxi School of Medicine, Jiangnan University, Wuxi, China.
Rong WangWuxi School of Medicine, Jiangnan University, Wuxi, China.
Lingling JiaWuxi School of Medicine, Jiangnan University, Wuxi, China.
Wei ChenSchool of Food Science and Technology, Jiangnan University, Wuxi, China.
Ninghan FengDepartment of Urology, Wuxi No. 2 People's Hospital, Wuxi, China.
Yong Q ChenWuxi School of Medicine, Jiangnan University, Wuxi, China.
Jiangnan University · CNWuxi No.2 People's Hospital · CN

Funding

Key Research and Development Program of Jiangsu Province BE2018624National First-class Discipline Program of Food Science and Technology JUFSTR20180101National Key Research and Development Program of China 2017YFD0400200The National Natural Science Foundation of China Grants 31471128The National Natural Science Foundation of China Grants 31771539
6 · The paper itself

Abstract

Alternative polarization of macrophages regulates multiple biological processes. While M1-polarized macrophages generally mediate rapid immune responses, M2-polarized macrophages induce chronic and mild immune responses. In either case, polyunsaturated fatty acid (PUFA)-derived lipid mediators act as both products and regulators of macrophages. Prostaglandin E

Indexed as

Cell DifferentiationAlprostadilAnimalsAnti-Inflammatory AgentsCell PolarityHumansInflammationMacrophage ActivationMaleMiceMice, Inbred C57BLProstatic NeoplasmsSignal TransductionAlprostadilAnti-Inflammatory Agentsprostaglandin E3macrophage polarizationprostaglandin E3protein kinase Atumour-associated macrophage

Identifiers

PMID33982835
PMCPMC8184682
OpenAlexW3160909981

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.