Evidence map›Paper›PMID 33982782›Full record

ArticleMolecular medicine reports2021

Overexpression of hsa_circ_0001445 reverses oxLDL‑induced inhibition of HUVEC proliferation via SRSF1.

Guiying Liang, Sihua Chen, Sha Xin, Liang Dong

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

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  9. Circular RNAs in vascular diseases.Frontiers in cardiovascular medicine · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Guiying LiangDepartment of Cardiology, First People's Hospital of Fuyang District, Hangzhou, Zhejiang 311400, P.R. China.
Sihua ChenDepartment of Cardiology, First People's Hospital of Fuyang District, Hangzhou, Zhejiang 311400, P.R. China.
Sha XinDepartment of Cardiology, First People's Hospital of Fuyang District, Hangzhou, Zhejiang 311400, P.R. China.
Liang DongDepartment of Cardiology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang 310009, P.R. China.
The First People's Hospital of Guiyang · CNSecond Affiliated Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is a primary cause of multiple types of cardiovascular disease, including myocardial infarction. In addition, injury of human umbilical vein endothelial cells (HUVECs) can lead to the development of atherosclerosis. Circular (circ)RNAs participate in atherosclerosis. It has previously been shown that circRNA cSMARCA5 (hsa_circ_0001445) expression is downregulated in atherosclerosis. However, the effects of hsa_circ_0001445 on the proliferation of HUVECs remain unclear. In order to mimic atherosclerosis

Indexed as

Apoptosisbeta CateninCell MovementCell ProliferationCells, CulturedEpithelial-Mesenchymal TransitionHumansHuman Umbilical Vein Endothelial CellsLipoproteins, LDLMembrane Potential, MitochondrialNeovascularization, PathologicRNA, CircularSerine-Arginine Splicing Factorsbeta CateninLipoproteins, LDLoxidized low density lipoproteinRNA, CircularSerine-Arginine Splicing FactorsSRSF1 protein, humanatherosclerosishsa_circ_0001445serine/arginine‑rich splicing factor 1β‑catenin

Identifiers

PMID33982782
PMCPMC8134882
OpenAlexW3161073066

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.