Evidence map›Paper›PMID 33982577›Full record

ArticlePhysiological research2021

C-reactive protein, chemerin, fetuin-A and osteopontin as predictors of cardiovascular risks in persons with psoriasis vulgaris.

P Borsky, Z Fiala, C Andrys, M Beranek, K Hamakova, J Kremlacek, A Malkova, T Svadlakova, J Krejsek, V Palicka and 3 more

Abstract read
In one paragraph

Article in Physiological research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. The Role of Selected Proteins in the Pathogenesis of Psoriasis.International journal of molecular sciences · 2025
    Review
  4. Article
  5. The Role of Osteopontin in Psoriasis-A Scoping Review.Journal of clinical medicine · 2024
    Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. The structure, biosynthesis, and biological roles of fetuin-A: A review.Frontiers in cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

P BorskyInstitute of Preventive Medicine, Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic. borka@lfhk.cuni.cz.
Z Fiala
C Andrys
M Beranek
K Hamakova
J Kremlacek
A Malkova
T Svadlakova
J Krejsek
V Palicka
V Rehacek
L Kotingova
L Borska

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study aimed to contribute to understanding the role of CRP, chemerin, fetuin-A and osteopontin and to assess their suitability as biomarkers of early stages of cardiovascular diseases in psoriasis vulgaris. Serum levels measured in 28 patients and 22 controls. Patients: increased levels of CRP (p<0.001), chemerin (p<0.05), osteopontin (p<0.05) and decreased levels of fetuin-A (p<0.05), significant relationships between CRP and fetuin-A (rho=0.530, p<0.01), CRP and chemerin (rho=0.543, p<0.01), CRP and age (rho=0.590, p<0.001), osteopontin and fetuin-A (r=-0.415, p<0.05), chemerin and PASI score (rho=-0.424, p<0.05). We confirmed specific roles of the biomarkers in psoriasis. CRP, fetuin-A and osteopontin could be considered appropriate markers for the detection of early stages of cardiovascular diseases.

Indexed as

Heart Disease Risk FactorsAdultalpha-2-HS-GlycoproteinBiomarkersBody Mass IndexCase-Control StudiesChemokinesC-Reactive ProteinFemaleHumansMaleMiddle AgedOsteopontinPsoriasisAHSG protein, humanalpha-2-HS-GlycoproteinBiomarkersChemokinesC-Reactive ProteinOsteopontinRARRES2 protein, humanSPP1 protein, human

Identifiers

PMID33982577
PMCPMC8820567

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.