Evidence map›Paper›PMID 33982438›Full record

ArticleClinical and translational science2021

Effects of 5-HT

Mitsuhiro Goda, Masaya Kanda, Toshihiko Yoshioka, Ami Yoshida, Yoichi Murai, Yoshito Zamami, Fuka Aizawa, Takahiro Niimura, Hirofumi Hamano, Naoto Okada and 4 more

Open access · goldAbstract read
In one paragraph

Article in Clinical and translational science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. A Novel Approach to Zero-Shot Drug-Drug Interaction Prediction Enabled by EHR-Augmented Knowledge Graphs.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2026
    Article
  3. Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Mitsuhiro GodaDepartment of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Masaya KandaDepartment of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Toshihiko YoshiokaDepartment of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Ami YoshidaDepartment of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Yoichi MuraiDepartment of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Yoshito ZamamiDepartment of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Fuka AizawaDepartment of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Takahiro NiimuraDepartment of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Hirofumi HamanoDepartment of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Naoto OkadaDepartment of Pharmacy, Tokushima University Hospital, Tokushima, Japan.
Kenta YagiClinical Research Center for Developmental Therapeutics, Tokushima University Hospital, Tokushima, Japan.
Masayuki ChumaDepartment of Pharmacy, Asahikawa Medical University Hospital, Hokkaido, Japan.
Yuki Izawa-IshizawaDepartment of Pharmacology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Keisuke IshizawaDepartment of Clinical Pharmacology and Therapeutics, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Tokushima University · JPTokushima University Hospital · JPAsahikawa Medical University · JP

Funding

Japan Society for the Promotion of Science (JSPS) KAKENHI 20H05799Japan Society for the Promotion of Science (JSPS) KAKENHI 20K07132
6 · The paper itself

Abstract

Nausea, vomiting, and renal injury are the common adverse effects associated with cisplatin. Cisplatin is excreted via the multidrug and toxin release (MATE) transporter, and the involvement of the MATE transporter in cisplatin-induced kidney injury has been reported. The MATE transporter is also involved in the excretion of ondansetron, but the effects of 5-HT

Indexed as

Acute Kidney InjuryAgedAnimalsBenzimidazolesCisplatinDisease Models, AnimalFemaleGranisetronHumansKidneyMaleMiceMiddle AgedNauseaOndansetronOrganic Cation Transport ProteinsBenzimidazolesCisplatinGranisetronOndansetronOrganic Cation Transport ProteinsPalonosetronramosetronSerotonin 5-HT3 Receptor Antagonists

Identifiers

PMID33982438
PMCPMC8504842
OpenAlexW3160830786

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.