ArticlePlant biotechnology journal2021
DELLA proteins BnaA6.RGA and BnaC7.RGA negatively regulate fatty acid biosynthesis by interacting with BnaLEC1s in Brassica napus.
Article in Plant biotechnology journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 29 citations in OpenAlex.
- The BnTFL1-BnJAM3-BnSWEETs Module Orchestrates Seed Storage Reserve Accumulation in Brassica napus.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Functional Characterisation of NF-YCs in True Leaf Biomass Accumulation.Plants (Basel, Switzerland) · 2026Article
- Mediator subunit MED25 represses ABI5-dependent activation of erucic acid biosynthetic geneFrontiers in plant science · 2026Article
- Plant oil biosynthesis and genetic improvement: progress, challenges, and opportunities.Plant physiology · 2025Review
- Analysis of lipidomics profile of Brassica napus hybrid 'Fangyou 777' and its parents during ripening stages based on UPLC-MS/MS.BMC plant biology · 2025Article
- Identification of transcription factor BnHDG4-A08 as a novel candidate associated with the accumulation of oleic, linoleic, linolenic, and erucic acid in Brassica napus.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- Unraveling the genetic basis of oil quality in olives: a comparative transcriptome analysis.Frontiers in plant science · 2024Article
- The current scenario and future perspectives of transgenic oilseed mustard by CRISPR-Cas9.Molecular biology reports · 2023Review
- A novel type of Brassica napus with higher stearic acid in seeds developed through genome editing of BnaSAD2 family.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Comparative transcriptome profiling reveals the multiple levels of crosstalk in phytohormone networks in Brassica napus.Plant biotechnology journal · 2023Article
- CRISPR-mediated technology for seed oil improvement in rapeseed: Challenges and future perspectives.Frontiers in plant science · 2023Review
- Study on molecular mechanism of volatiles variation duringFrontiers in plant science · 2023Article
- Genome-Wide Identification and Expression Analysis ofInternational journal of molecular sciences · 2022Article
- Auxin-regulated timing of transition from vegetative to reproductive growth in rapeseed (Frontiers in plant science · 2022Article
- DELLA proteins BnaA6.RGA and BnaC7.RGA negatively regulate fatty acid biosynthesis by interacting with BnaLEC1s in Brassica napus.Plant biotechnology journal · 2021Article
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Authors and funding
12 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seed oil content (SOC) and fatty acid (FA) composition determine the quality and economic value of rapeseed (Brassica napus). Little is known about the role of gibberellic acid (GA) in regulating FA biosynthesis in B. napus. Here, we discovered that four BnaRGAs (B. napus REPRESSOR OF GA), encoding negative regulators of GA signalling, were suppressed during seed development. Compared to the wild type, SOC was reduced in gain-of-function mutants bnaa6.rga-D and ds-3, which also showed reduced oleic acid and increased linoleic acid contents. By contrast, the loss-of-function quadruple mutant bnarga displayed higher SOC during early seed development than the wild type, with increased oleic acid and reduced linoleic acid contents. Notably, only BnaA6.RGA and BnaC7.RGA physically interacted with two BnaLEC1s, which function as essential transcription factors in FA biosynthesis. The FA composition did not significantly differ between bnarga bnalec1 sextuple mutants and bnalec1, suggesting that BnaLEC1s are epistatic to BnaRGAs in the regulation of FA composition. Furthermore, BnaLEC1-induced activation of BnaABI3 expression was repressed by BnaA6.RGA, indicating that GA triggers the degradation of BnaRGAs to relieve their repression of BnaLEC1s, thus promoting the transcription of downstream genes to facilitate oil biosynthesis. Therefore, we uncovered a developmental stage-specific role of GA in regulating oil biosynthesis via the GA-BnaRGA-BnaLEC1 signalling cascade, providing a novel mechanistic understanding of how phytohormones regulate FA biosynthesis in seeds. BnaRGAs represent promising targets for oil crop improvement.
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