ReviewPituitary2021
Treatment and prognostic factors of pituicytoma: a single-center experience and comprehensive literature review.
Review in Pituitary, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 19 citations in OpenAlex.
- Pituicytoma in the third ventricle suggesting a third ventricular floor origin: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Posterior Pituitary and Hypothalamic Neuronal Tumors in the 5th WHO Classification: Molecular Insights, Diagnostic Markers, and Clinical Management.International journal of molecular sciences · 2026Review
- Preoperative Prediction of Non-functional Pituitary Neuroendocrine Tumors and Posterior Pituitary Tumors Based on MRI Radiomic Features.Journal of imaging informatics in medicine · 2026Article
- Case Report: Rare collision tumors: ACTH-secreting pituitary neuroendocrine tumor and pituicytoma - histopathological and ultrastructural analysis.Frontiers in endocrinology · 2026Article
- Machine learning method based on radiomics help differentiate posterior pituitary tumors from pituitary neuroendocrine tumors and craniopharyngioma.Scientific reports · 2025Article
- Posterior pituitary tumors: an entity unto itself.Pituitary · 2025Article
- A Rare Case of Pituicytoma During Pregnancy.JCEM case reports · 2025Article
- Clinical, surgical, and endocrine outcome following treatment of posterior pituitary tumors: a retrospective cohort study.Pituitary · 2025Article
- Posterior transpetrosal approach to a suprasellar retroinfundibular pituicytoma: A case report and comprehensive literature review.Brain & spine · 2025Article
- Intraventricular pituicytoma: illustrative case.Journal of neurosurgery. Case lessons · 2024Article
- Surgical approach to the treatment of pituicytoma. Report of five cases and a literature review.World neurosurgery: X · 2023Article
- Surgical management of pituicytomas: a single-center case series.Acta neurologica Belgica · 2023Article
- Pituicytoma: A rare tumor of the sella. A case report and review of literature for diagnosis and management.Surgical neurology international · 2023Article
- Pituicytoma: A rare case report of sellar and suprasellar tumor.International journal of surgery case reports · 2022Article
- Pituicytoma Associated with Suspected Cushing's Disease: Two Case Reports and a Literature Review.Journal of clinical medicine · 2022Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
purposePreoperative diagnosis of pituicytomas is difficult, and management and prognostic factors remain ambiguous. The purpose of this study was to elucidate the radiological characteristics of pituicytoma, to assess the risk factors affecting tumor progression, and to propose the optimal treatment regimen based on comprehensive analysis.
methodsWe reviewed the clinical data of 22 patients with pituicytoma confirmed pathologically in our institution. In addition, 93 cases of pituicytoma in the previous literature were recruited. The individual data of 115 patients were analyzed to evaluate the adverse factors affecting pituicytoma progression.
resultsIn the combined cohort, 3 of 61 patients who underwent gross-total resection (GTR) developed recurrence (4.9%); of the 54 patients who received non-GTR, 19 progressed (35.2%). Univariate and multivariate Cox regression analysis verified male gender (HR 2.855, 95% CI 1.008-8.089; p = 0.048), TS (transsphenoidal surgery; HR 3.559, 95% CI 1.015-12.476; p = 0.047), and non-GTR (HR 4.388, 95%CI 1.240-15.521; p = 0.022) were independent unfavorable factors for pituicytoma progression. A multivariate logistic regression model verified that tumor diameter ≥ 1.85 cm (OR 4.859, 95% CI 1.335-17.691; p = 0.016) was independent adverse factors for GTR. Compared with TS, OT (open transcranial) is more likely to have postoperative complications (OR 3.185, 95% CI 1.020-9.944; p = 0.046), especially vision deterioration (OR 37.267, 95% CI 4.486-309.595; p = 0.001).
conclusionBased on our findings, GTR was advocated as an optimal treatment for pituicytomas. However, in order to avoid damage to important structures, partial resection is acceptable. After that, adjuvant radiotherapy is recommended for male patients with high Ki-67 index, and the remaining patients can be followed up closely. When the tumor recurs or progresses, it is recommended to re-operate and remove the lesion completely as far as possible. If GTR is still not possible, postoperative radiotherapy for the residual tumor is recommended.
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