Evidence map›Paper›PMID 33982192›Full record

ReviewJournal, genetic engineering & biotechnology2021

Secondary metabolites and biodiversity of actinomycetes.

Manal Selim Mohamed Selim, Sayeda Abdelrazek Abdelhamid, Sahar Saleh Mohamed

Open access · diamondAbstract readReview
In one paragraph

Review in Journal, genetic engineering & biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 1 pooled it
28.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 1 synthesis or guideline pooled it, 280 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Bioprospecting Indoor Bacteria Producing Bioactive Metabolites.Environmental microbiology reports · 2026
    Article
  4. Article
  5. Production of Biosurfactant byInternational journal of molecular sciences · 2026
    Article
  6. Article
  7. Article
  8. Porous FeNanomaterials (Basel, Switzerland) · 2026
    Article
  9. Article
  10. Article
  11. Microbial Landscape of Bull (Animals : an open access journal from MDPI · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. ExploringMicrobiology (Reading, England) · 2026
    Review
  17. Article
  18. Actinomycetes in the spotlight: biodiversity and their role in bioremediation.World journal of microbiology & biotechnology · 2026
    Review
  19. Discovery of a New Rosamicin Derivative from EndophyticMolecules (Basel, Switzerland) · 2026
    Article
  20. Review

57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Manal Selim Mohamed SelimMicrobial Biotechnology Department-Genetic Engineering Division, National Research Centre, Giza, Egypt.
Sayeda Abdelrazek AbdelhamidMicrobial Biotechnology Department-Genetic Engineering Division, National Research Centre, Giza, Egypt. sayeda.abdelrazek@yahoo.com.
Sahar Saleh MohamedMicrobial Biotechnology Department-Genetic Engineering Division, National Research Centre, Giza, Egypt.
National Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe ability to produce microbial bioactive compounds makes actinobacteria one of the most explored microbes among prokaryotes. The secondary metabolites of actinobacteria are known for their role in various physiological, cellular, and biological processes. MAIN BODY: Actinomycetes are widely distributed in natural ecosystem habitats such as soil, rhizosphere soil, actinmycorrhizal plants, hypersaline soil, limestone, freshwater, marine, sponges, volcanic cave-hot spot, desert, air, insects gut, earthworm castings, goat feces, and endophytic actinomycetes. The most important features of microbial bioactive compounds are that they have specific microbial producers: their diverse bioactivities and their unique chemical structures. Actinomycetes represent a source of biologically active secondary metabolites like antibiotics, biopesticide agents, plant growth hormones, antitumor compounds, antiviral agents, pharmacological compounds, pigments, enzymes, enzyme inhibitors, anti-inflammatory compounds, single-cell protein feed, and biosurfactant. SHORT

conclusionsFurther highlight that compounds derived from actinobacteria can be applied in a wide range of industrial applications in biomedicines and the ecological habitat is under-explored and yet to be investigated for unknown, rare actinomycetes diversity.

Indexed as

ActinomycetesBioactive compoundBiodiversitySecondary metabolites

Identifiers

PMID33982192
PMCPMC8116480
OpenAlexW3160377855

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.