Evidence map›Paper›PMID 33982189›Full record

ArticleWorld journal of surgery2021

Rates of Bile Acid Diarrhoea After Cholecystectomy: A Multicentre Audit.

Alexia Farrugia, Joseph Anthony Attard, Stuart Hanmer, Stuart Bullock, Siobhan McKay, Marwa Al-Azzawi, Roshneen Ali, Giles Bond-Smith, Ben Colleypriest, Sarah Dyer and 14 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in World journal of surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Diagnosis and treatment of post-cholecystectomy diarrhoea.World journal of gastrointestinal surgery · 2023
    Review
  7. Article
  8. Review
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 6 institutions in 1 country.

Alexia FarrugiaDepartment of Gastroenterology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.ORCID 0000-0002-4366-9068
Joseph Anthony AttardLincoln University Hospitals, Lincoln, UK.
Stuart HanmerDepartment of Gastroenterology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.
Stuart BullockDepartment of Gastroenterology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.
Siobhan McKayDepartment of Gastroenterology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.
Marwa Al-AzzawiQueen Elizabeth University Hospitals, Glasgow, UK.
Roshneen AliOxford University Hospitals NHS Trust, Oxford, UK.
Giles Bond-SmithOxford University Hospitals NHS Trust, Oxford, UK.
Ben ColleypriestRoyal United Hospitals Bath NHS Trust, Avon, UK.
Sarah DyerNorth Bristol NHS Trust, Bristol, UK.
Benjamin MastermanRoyal United Hospitals Bath NHS Trust, Avon, UK.
Michael OkochaNorth Bristol NHS Trust, Bristol, UK.
Alan OsborneNorth Bristol NHS Trust, Bristol, UK.
Rikhilroy PatelOxford University Hospitals NHS Trust, Oxford, UK.
Mahmoud SallamOxford University Hospitals NHS Trust, Oxford, UK.
Emmanuel SelverajOxford University Hospitals NHS Trust, Oxford, UK.
Samar ShalabyOxford University Hospitals NHS Trust, Oxford, UK.
Wenrui SunOxford University Hospitals NHS Trust, Oxford, UK.
Fraser ToddNorth Bristol NHS Trust, Bristol, UK.
Joel WardOxford University Hospitals NHS Trust, Oxford, UK.
Rebecca WindleOxford University Hospitals NHS Trust, Oxford, UK.
Saboor KhanDepartment of Gastroenterology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.
Nigel WilliamsDepartment of Gastroenterology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.
Ramesh P ArasaradnamDepartment of Gastroenterology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK. R.Arasaradnam@warwick.ac.uk.
Oxford University Hospitals NHS Trust · GBUniversity Hospitals Coventry and Warwickshire NHS Trust · GBNorth Bristol NHS Trust · GBRoyal United Hospital Bath NHS Trust · GBLincoln County Hospital · GBQueen Elizabeth University Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBile acid diarrhoea (BAD) can occur due to disruption to the enterohepatic circulation, e.g. following cholecystectomy. Post-cholecystectomy diarrhoea has been reported in 2.1-57.2% of patients; however, this is not necessarily due to BAD. The aim of this study was to determine the rates of bile acid diarrhoea diagnosis after cholecystectomy and to consider investigation practices.

methodsA retrospective analysis of electronic databases from five large centres detailing patients who underwent laparoscopic cholecystectomy between 2013 and 2017 was cross-referenced with a list of patients who underwent

resultsA total of 9439 patients underwent a laparoscopic cholecystectomy between 1 January 2013 and 31 December 2017 in the five centres. In total, 202 patients (2.1%) underwent investigation for diarrhoea via DISCUSSION/

conclusionOnly a small proportion of patients, post-cholecystectomy, were investigated for diarrhoea with significant time delay to diagnosis. The true prevalence of BAD after cholecystectomy may be much higher, and clinicians need to have an increased awareness of this condition due to its amenability to treatment.

Indexed as

Bile Acids and SaltsDiarrheaCholecystectomyHumansPrevalenceRetrospective StudiesBile Acids and Salts

Identifiers

PMID33982189
PMCPMC8236047
OpenAlexW3162787681

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.