Evidence map›Paper›PMID 33982126›Full record

SynthesisThe Journal of nutrition2021

Patterns of Growth in Childhood in Relation to Adult Schooling Attainment and Intelligence Quotient in 6 Birth Cohorts in Low- and Middle-Income Countries: Evidence from the Consortium of Health-Oriented Research in Transitioning Societies (COHORTS).

Natalia E Poveda, Fernando P Hartwig, Cesar G Victora, Linda S Adair, Fernando C Barros, Santosh K Bhargava, Bernardo L Horta, Nanette R Lee, Reynaldo Martorell, Mónica Mazariegos and 8 more

Open access · hybridAbstract readMeta-Analysis
In one paragraph

Synthesis in The Journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 7 countries.

Natalia E PovedaNutrition and Health Sciences, Laney Graduate School, Emory University, Atlanta, GA, USA.ORCID 0000-0001-6070-362X
Fernando P HartwigPostgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.ORCID 0000-0003-3729-0710
Cesar G VictoraPostgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.ORCID 0000-0002-2465-2180
Linda S AdairDepartment of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID 0000-0002-3670-8073
Fernando C BarrosPostgraduate Program in Health and Behaviour, Universidade Católica de Pelotas, Pelotas, Brazil.ORCID 0000-0001-5973-1746
Santosh K BhargavaConsultant Pediatrician and Founder New Delhi Birth Cohort, New Delhi, India.
Bernardo L HortaPostgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.ORCID 0000-0001-9843-412X
Nanette R LeeUSC-Office of Population Studies Foundation, Inc, University of San Carlos - TC, Talamban, Cebu City, Cebu, Philippines.
Reynaldo MartorellNutrition and Health Sciences, Laney Graduate School, Emory University, Atlanta, GA, USA.ORCID 0000-0001-8862-7243
Mónica MazariegosINCAP Research Center for the Prevention of Chronic Diseases (CIIPEC), Institute of Nutrition of Central America and Panama (INCAP), Guatemala City, Guatemala.ORCID 0000-0002-2250-3683
Ana M B MenezesPostgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.ORCID 0000-0002-2996-9427
Shane A NorrisSAMRC Developmental Pathways for Health Research Unit, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0001-7124-3788
Linda M RichterDSI-NRF Centre of Excellence in Human Development, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-3654-3192
Harshpal Singh SachdevSenior Consultant Pediatrics and Clinical Epidemiology, Sitaram Bhartia Institute of Science and Research, New Delhi, India.ORCID 0000-0002-4956-9391
Alan SteinDepartment of Psychiatr, University of Oxford, Oxford, United Kingdom.ORCID 0000-0001-8207-2822
Fernando C WehrmeisterPostgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.ORCID 0000-0001-7137-1747
Aryeh D SteinNutrition and Health Sciences, Laney Graduate School, Emory University, Atlanta, GA, USA.ORCID 0000-0003-1138-6458
COHORTS Group
Universidade Federal de Pelotas · BREmory University · USInstitute of Nutrition of Central America and Panama · GTSitaram Bhartia Institute of Science and Research · INSouth African Medical Research Council · ZAUniversidade Católica de Pelotas · BRUniversity of North Carolina at Chapel Hill · USUniversity of San Carlos · PHUniversity of the Witwatersrand · ZA

Funding

British Heart Foundation UKPG/05/046Medical Research Council MC_UP_A620_1016Medical Research Council MC_UU_12011/3Wellcome TrustWellcome Trust 086974/Z/08/Z
6 · The paper itself

Abstract

backgroundGrowth faltering has been associated with poor intellectual performance. The relative strengths of associations between growth in early and in later childhood remain underexplored.

objectivesWe examined the association between growth in childhood and adult human capital in 5 low- and middle-income countries (LMICs).

methodsWe analyzed data from 9503 participants in 6 prospective birth cohorts from 5 LMICs (Brazil, Guatemala, India, the Philippines, and South Africa). We used linear and quasi-Poisson regression models to assess the associations between measures of height and relative weight at 4 age intervals [birth, age ∼2 y, midchildhood (MC), adulthood] and 2 dimensions of adult human capital [schooling attainment and Intelligence Quotient (IQ)].

resultsMeta-analysis of site- and sex-specific estimates showed statistically significant associations between size at birth and height at ∼2 y and the 2 outcomes (P < 0.001). Weight and length at birth and linear growth from birth to ∼2 y of age (1 z-score difference) were positively associated with schooling attainment (β: 0.13; 95% CI: 0.08, 0.19, β: 0.17; 95% CI: 0.07, 0.32, and β: 0.25, 95% CI: 0.10, 0.40, respectively) and adult IQ (β: 0.74, 95% CI: 0.35, 1.14, β: 0.73, 95% CI: 0.35, 1.10, and β: 1.52, 95% CI: 0.96, 2.08, respectively). Linear growth from age 2 y to MC and from MC to adulthood was not associated with higher school attainment or IQ. Change in relative weight in early childhood, MC, and adulthood was not associated with either outcome.

conclusionsLinear growth in the first 1000 d is a predictor of schooling attainment and IQ in adulthood in LMICs. Linear growth in later periods was not associated with either of these outcomes. Changes in relative weight across the life course were not associated with schooling and IQ in adulthood.

Indexed as

Birth CohortDeveloping CountriesAdultChild, PreschoolEducational StatusFemaleHumansInfant, NewbornIntelligenceMaleProspective Studiescohort studiesconditional heightconditional relative weightgrowthintelligence quotientschooling attainment

Identifiers

PMID33982126
PMCPMC8436131
OpenAlexW3160692583

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.