ArticleiScience2021
Bi-directional encoding of context-based odors and behavioral states by the nucleus of the lateral olfactory tract.
Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Encoding of odor information and reward anticipation in anterior cortical amygdaloid nucleus.iScience · 2026Article
- Collateralization patterns of principal basolateral amygdala neurons delineate distinct output streams.iScience · 2025Article
- Synaptic Connectivity and Electrophysiological Properties of the Nucleus of the Lateral Olfactory Tract.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- An intra-oral flavor detection task in freely moving mice.iScience · 2024Article
- Neuronal types in the mouse amygdala and their transcriptional response to fear conditioning.Nature neuroscience · 2023Article
- Hippocampal CA1 Neurons Represent Positive Feedback During the Learning Process of an Associative Memory Task.Frontiers in systems neuroscience · 2021Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The nucleus of the lateral olfactory tract (NLOT) is not only a part of the olfactory cortex that receives olfactory sensory inputs but also a part of the cortical amygdala, which regulates motivational behaviors. To examine how neural activity of the NLOT is modulated by decision-making processes that occur during various states of learned goal-directed behaviors, we recorded NLOT spike activities of mice performing odor-guided go/no-go tasks to obtain a water reward. We observed that several NLOT neurons exhibited sharp go-cue excitation and persistent no-go-cue suppression responses triggered by an odor onset. The bidirectional cue encoding introduced NLOT population response dynamics and provided a high odor decoding accuracy before executing cue-odor-evoked behaviors. The go-cue responsive neurons were also activated in the reward drinking state, indicating context-based odor-outcome associations. These findings suggest that NLOT neurons play an important role in the translation from context-based odor information to appropriate behavior.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.