Evidence map›Paper›PMID 33981967›Full record

ArticleiScience2021

Interpretable deep learning for automatic diagnosis of 12-lead electrocardiogram.

Dongdong Zhang, Samuel Yang, Xiaohui Yuan, Ping Zhang

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
19.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 180 citations in OpenAlex.

  1. Article
  2. [Multi-lead electrocardiogram atrial fibrillation detection algorithm based on multi-scale patch-based attention].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
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  7. [Evaluation of an interpretable 12-lead ECG automatic diagnosis model based on deep feature fusion].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
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  9. [ResLSTM-TemporalSE: an automated classification model for multi-lead ECG signals].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Dongdong ZhangDepartment of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.
Samuel YangDepartment of Internal Medicine, Division of Hospital Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Xiaohui YuanSchool of Computer Science and Technology, Wuhan University of Technology, Wuhan, Hubei, China.
Ping ZhangDepartment of Biomedical Informatics, The Ohio State University, Columbus, OH, USA.
Wuhan University of Technology · CNNationwide Children's Hospital · USThe Ohio State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electrocardiogram (ECG) is a widely used reliable, non-invasive approach for cardiovascular disease diagnosis. With the rapid growth of ECG examinations and the insufficiency of cardiologists, accurate and automatic diagnosis of ECG signals has become a hot research topic. In this paper, we developed a deep neural network for automatic classification of cardiac arrhythmias from 12-lead ECG recordings. Experiments on a public 12-lead ECG dataset showed the effectiveness of our method. The proposed model achieved an average F1 score of 0.813. The deep model showed superior performance than 4 machine learning methods learned from extracted expert features. Besides, the deep models trained on single-lead ECGs produce lower performance than using all 12 leads simultaneously. The best-performing leads are lead I, aVR, and V5 among 12 leads. Finally, we employed the SHapley Additive exPlanations method to interpret the model's behavior at both the patient level and population level.

Indexed as

Artificial IntelligenceClinical FindingMedicine

Identifiers

PMID33981967
PMCPMC8082080
OpenAlexW3142998727

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.