Evidence map›Paper›PMID 33981936›Full record

ReviewPain reports2021

Prognostic factors for pain chronicity in low back pain: a systematic review.

Linda Karoliina Nieminen, Liisa Maria Pyysalo, Markku Juhani Kankaanpää

2 registry-linked trialsOpen access · goldAbstract readReview
In one paragraph

Review in Pain reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 130 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
130citing papers in PubMed, 2 pooled it
31.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07026097 narecruitingnot on this mapstarted 2025, after this paper: background citation

Effects of Online Versus Physically Supervised Pilates Exercise Program With Common Standard Physical Therapy Treatment on Pain, Mobility and Function in Patients With Non-specific Low Back Pain

TypeinterventionalSponsorRiphah International UniversityRan2025 to 2025Enrolled40ConditionsLow Back PainArmsPilates Exercise - Online, Pilates Exercise - Supervised
NCT07403292 nacompletednot on this mapstarted 2025, after this paper: background citation

Comparative Effects of McGill and McKenzie Exercises on Pain, Range of Motion and Disability in Patients With Chronic Mechanical Low Back Pain

TypeinterventionalSponsorRiphah International UniversityRan2025 to 2025Enrolled57ConditionsChronic Mechanical Low Back PainArmsMcGill Exercises, McKenzie Exercises, Standardized Physiotherapy Treatment
3 · Its place in the literature

Who cites it

130 citing papers in PubMed, 2 syntheses or guidelines pooled it, 263 citations in OpenAlex.

  1. Pooled it
  2. Causal effects of psychosocial factors on chronic back pain: a bidirectional Mendelian randomisation study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2022
    Pooled it
  3. Trial
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  5. Impact of 3-dimensional myofascial release on tumor necrosis factor (TNF) alpha biomarker in nonspecific low back pain: a randomised controlled trial.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Trial
  6. Trial
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  10. Article
  11. Article
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  14. Understanding the burden of chronic back pain: a spatial microsimulation of chronic back pain at small area level across England.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  15. Article
  16. Physiotherapy informed by acceptance and commitment therapy for chronic low back pain: A randomized trial.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2026
    Article
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  20. Article

70 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Linda Karoliina NieminenDepartment of Rehabilitation and Psychosocial Support, Tampere University Hospital, Tampere, Finland.
Liisa Maria PyysaloDepartment of Rehabilitation and Psychosocial Support, Tampere University Hospital, Tampere, Finland.
Markku Juhani KankaanpääDepartment of Rehabilitation and Psychosocial Support, Tampere University Hospital, Tampere, Finland.
Tampere University Hospital · FITampere University · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low back pain is the leading cause for years lived in disability. Most people with acute low back pain improve rapidly, but 4% to 25% of patients become chronic. Since the previous systematic reviews on the subject, a large number of new studies have been conducted. The objective of this article was to review the evidence of the prognostic factors behind nonspecific chronic low back pain. A systematic literature search was performed without date limitation from the MEDLINE, Cochrane library, and Medic databases. Specific inclusion criteria were used, and risk factors before the onset of chronic symptoms were searched. Study quality was assessed by 2 independent reviewers. One hundred eleven full articles were read for potential inclusion, and 25 articles met all the inclusion criteria. One study was rated as good quality, 19 studies were rated as fair quality, and 5 articles were rated as poor quality. Higher pain intensity, higher body weight, carrying heavy loads at work, difficult working positions, and depression were the most frequently observed risk factors for chronic low back pain. Maladaptive behavior strategies, general anxiety, functional limitation during the episode, smoking, and particularly physical work were also explicitly predictive of chronicity. According to this systematic review, several prognostic factors from the biomechanical, psychological and psychosocial point of view are significant for chronicity in low back pain.

Indexed as

Chronic painLow back painNonspecificPrognostic factorsRisk factors

Identifiers

PMID33981936
PMCPMC8108595
OpenAlexW3152547100

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.