Evidence map›Paper›PMID 33981828›Full record

ArticleMolecular therapy oncolytics2021

circBANP promotes colorectal cancer growth and metastasis via sponging let-7d-5p to modulate HMGA1/Wnt/β-catenin signaling.

Yijiang Ni, Chen Lu, Wulin Wang, Wenjie Gao, Chunzhao Yu

Open access · goldAbstract read
In one paragraph

Article in Molecular therapy oncolytics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yijiang NiDepartment of General Surgery, The Second Affiliated Hospital, Nanjing Medical University, Nanjing 210000, Jiangsu Province, P.R. China.
Chen LuDepartment of General Surgery, The Second Affiliated Hospital, Nanjing Medical University, Nanjing 210000, Jiangsu Province, P.R. China.
Wulin WangDepartment of General Surgery, The Second Affiliated Hospital, Nanjing Medical University, Nanjing 210000, Jiangsu Province, P.R. China.
Wenjie GaoDepartment of General Surgery, The Second Affiliated Hospital, Nanjing Medical University, Nanjing 210000, Jiangsu Province, P.R. China.
Chunzhao YuDepartment of General Surgery, The Second Affiliated Hospital, Nanjing Medical University, Nanjing 210000, Jiangsu Province, P.R. China.
Second Affiliated Hospital of Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer (CRC) is one of the most common and deadly cancers, and the incidence of CRC is on the rise. Due to the lack of early diagnosis method and high metastasis of the disease, the prognosis of CRC remains very poor. Exploring the underlying molecular mechanisms of CRC is very necessary for effective therapy. In this study, we investigated the function of circBANP in CRC. The results showed that circBANP was elevated in both CRC tissues and cells and its level positively correlated with the stage of CRC. Knockdown of circBANP greatly suppressed the epithelial-mesenchymal transition (EMT) process and CRC cell proliferation, migration, and invasion. In addition, knockdown of circBANP inhibited CRC tumor growth and metastasis

Indexed as

circBANPCRCEMTHMGA1let-7d-5pWnt/β-catenin

Identifiers

PMID33981828
PMCPMC8079336
OpenAlexW3138932163

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.