Evidence map›Paper›PMID 33981826›Full record

ReviewMolecular therapy oncolytics2021

A brief review of reporter gene imaging in oncolytic virotherapy and gene therapy.

Susanna C Concilio, Stephen J Russell, Kah-Whye Peng

Abstract readReview
In one paragraph

Review in Molecular therapy oncolytics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Optimization of CEST MRI Reporter Protein Design Using Cation-Pi Networks.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. International journal of stem cells · 2023
    Review
  11. Review
  12. Review
  13. Molecular MRI-Based Monitoring of Cancer Immunotherapy Treatment Response.International journal of molecular sciences · 2023
    Review
  14. Article
  15. Reporter Genes for Brain Imaging Using MRI, SPECT and PET.International journal of molecular sciences · 2022
    Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Susanna C ConcilioDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Stephen J RussellDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.
Kah-Whye PengDepartment of Molecular Medicine, Mayo Clinic, Rochester, MN 55905, USA.

Funding

Women's Cancer ProgramP30CA015083 · NCI · MAYO CLINIC ROCHESTER · PI AKHILESH PANDEY · 1985 to 2026
$151.3M
Project 4: Targeting Resistance to T-Cell Directed Therapy in Multiple MyelomaP50CA186781 · NCI · MAYO CLINIC ARIZONA · PI Peter Leif Bergsagel · 2015 to 2026
$25.5M
Phase 2: NIS proteins with altered anion specificityR44TR001191 · NCATS · IMANIS LIFE SCIENCES, LLC · PI RUSSELL, STEPHEN J, SUKSANPAISAN, LUKKANA · 2017 to 2018
$1.5M
NCATS NIH HHS R44 TR001191NCI NIH HHS P30 CA015083NCI NIH HHS P50 CA186781
6 · The paper itself

Abstract

Reporter gene imaging (RGI) can accelerate development timelines for gene and viral therapies by facilitating rapid and noninvasive

Indexed as

bioluminescenceCerenkov luminescencefluorescencegene therapymagnetic resonance imagingmolecular imagingMRInuclear imagingoncolytic virotherapyoptical imagingPETphotoacoustic imagingpositron emission tomographyreporter gene imagingsingle photon emission computed tomographySPECTviral vectors

Identifiers

PMID33981826
PMCPMC8065251

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.