Evidence map›Paper›PMID 33981754›Full record

ArticleVisceral medicine2021

A Single-Center Case Series of Endoscopically Treated Aorto-Gastrointestinal Fistula after Endovascular Aortic Repair: Surgery Is Still the Only Valid Solution.

Alica Kubesch, Oliver Waidmann, Irina Blumenstein, Wolf Otto Bechstein, Mireen Friedrich-Rust, Michael Jung, Jörg Albert, Johannes Hausmann

Open access · bronzeAbstract read
In one paragraph

Article in Visceral medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Alica KubeschDepartment of Internal Medicine 1, Goethe-University Hospital Frankfurt, Frankfurt, Germany.
Oliver WaidmannDepartment of Internal Medicine 1, Goethe-University Hospital Frankfurt, Frankfurt, Germany.
Irina BlumensteinDepartment of Internal Medicine 1, Goethe-University Hospital Frankfurt, Frankfurt, Germany.
Wolf Otto BechsteinDepartment of General and Visceral Surgery, Goethe-University Hospital Frankfurt, Frankfurt, Germany.
Mireen Friedrich-RustDepartment of Internal Medicine 1, Goethe-University Hospital Frankfurt, Frankfurt, Germany.
Michael JungDepartment of Internal Medicine 1, Goethe-University Hospital Frankfurt, Frankfurt, Germany.
Jörg AlbertDepartment of Internal Medicine 1, Goethe-University Hospital Frankfurt, Frankfurt, Germany.
Johannes HausmannDepartment of Internal Medicine 1, Goethe-University Hospital Frankfurt, Frankfurt, Germany.
Goethe University Frankfurt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAortoesophageal fistula (AEF) is a life-threatening complication associated with endovascular aortic repair (EVAR) and occurs mostly in patients who undergo thoracic EVAR (TEVAR). To date, surgical treatment of AEF has been considered the most promising therapeutic approach. New endoscopic techniques could contribute to the therapy of AEF. The aim of this study was to analyze the outcome after endoscopic treatment of EVAR-associated AEF.

methodsAll patients who received endoscopic diagnostics and/or therapy for AEF after EVAR/TEVAR in our center between 2010 and 2019 were evaluated.

resultsSeven suitable patients were included. Six of them had undergone TEVAR and 1 had EVAR. Fistula occurred at an average of 307 days (range 21-2,774 days) post-EVAR. Endoscopic treatment was performed on 4 patients by using an over-the-scope clip (OTSC®). However, fistula recurred in all patients who were initially treated endoscopically. They were then treated either by sequential application of further OTSCs® or by implantation of a fully coated, self-expanding metal stent. One of these patients underwent a partial esophageal resection in a subsequent treatment approach. All patients died during the observational period, 5 as a direct consequence of the AEF/aortoduodenal fistula and 2 due to comorbidities. The median survival time after fistula occurrence was 120 days (range 5-823 days).

conclusionEndoscopic treatment of AEF with OTSC® should be considered as a possible interim solution, especially in patients with severe comorbidities. However, surgical remediation still appears to be the only procedure with intermediate to long-term therapeutic success.

Indexed as

Aortoesophageal fistula (AEF)EndoscopyEndovascular aortic repair (EVAR)FistulaOTSC®StentTEVAR

Identifiers

PMID33981754
PMCPMC8077538
OpenAlexW3038629083

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.