Evidence map›Paper›PMID 33981736›Full record

ArticleFrontiers in cardiovascular medicine2021

Serial EXTEM, FIBTEM, and tPA Rotational Thromboelastometry Observations in the Maastricht Intensive Care COVID Cohort-Persistence of Hypercoagulability and Hypofibrinolysis Despite Anticoagulation.

Anne-Marije Hulshof, Renée A G Brüggemann, Mark M G Mulder, Tom W van de Berg, Jan-Willem E M Sels, Renske H Olie, Bart Spaetgens, Alexander S Streng, Paul Verhezen, Iwan C C van der Horst and 4 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Reference Intervals for ROTEM-tPA: Whole-Blood Fibrinolysis Assessment in Healthy Adults.TH open : companion journal to thrombosis and haemostasis · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Monitoring of myocardial injury by serial measurements of QRS area and T area: The MaastrICCht cohort.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Rotational Thromboelastometry (ROTEMJournal of clinical medicine · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Anne-Marije HulshofCentral Diagnostic Laboratory, Maastricht University Medical Centre+, Maastricht, Netherlands.
Renée A G BrüggemannDepartment of Internal Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands.
Mark M G MulderDepartment of Intensive Care Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands.
Tom W van de BergCardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherlands.
Jan-Willem E M SelsDepartment of Intensive Care Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands.
Renske H OlieCardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherlands.
Bart SpaetgensDepartment of Internal Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands.
Alexander S StrengCentral Diagnostic Laboratory, Maastricht University Medical Centre+, Maastricht, Netherlands.
Paul VerhezenCentral Diagnostic Laboratory, Maastricht University Medical Centre+, Maastricht, Netherlands.
Iwan C C van der HorstCardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherlands.
Hugo Ten CateCardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherlands.
Henri M H SpronkCardiovascular Research Institute Maastricht, Maastricht University, Maastricht, Netherlands.
Bas C T van BusselDepartment of Intensive Care Medicine, Maastricht University Medical Centre+, Maastricht, Netherlands.
Yvonne M C HenskensCentral Diagnostic Laboratory, Maastricht University Medical Centre+, Maastricht, Netherlands.
Maastricht University Medical Centre · NLMaastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19fibrinolysispulmonary embolismthromboelastometry (ROTEM®)thrombosis

Identifiers

PMID33981736
PMCPMC8107372
OpenAlexW3162739727

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.