ArticleFrontiers in medicine2021
Outcomes of Sepsis and Septic Shock in Cancer Patients: Focus on Lactate.
Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 14 citations in OpenAlex.
- Shadow-Calibrated Stereo Vision for Colorimetric Sweat Analysis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Prognostic Factors and Risk Stratification in Malignant Tumor Patients With Sepsis: A Retrospective Cohort Study.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Predictive value of baseline levels and early dynamic changes of ctDNA for 28-day mortality in ICU patients with advanced lung cancer: a prospective single-center cohort study.Frontiers in molecular biosciences · 2026Article
- Survival of Patients with Solid Tumours and Sepsis Admitted to Intensive Care in a Tertiary Oncology Centre: A Retrospective Analysis.Journal of intensive care medicine · 2025Article
- A Comprehensive Review of Advanced Lactate Biosensor Materials, Methods, and Applications in Modern Healthcare.Sensors (Basel, Switzerland) · 2025Review
- Observational
- Association between site of infection and mortality in patients with cancer with sepsis or septic shock: A retrospective cohort study.Experimental and therapeutic medicine · 2023Article
- The effect of NK cell therapy on sepsis secondary to lung cancer: A case report.Open life sciences · 2023Article
- Early predicting 30-day mortality in sepsis in MIMIC-III by an artificial neural networks model.European journal of medical research · 2022Article
- Article
- Impact of cancer on mortality rates in patients with sepsis: A meta-analysis and meta-regression of current studies.World journal of clinical cases · 2022Article
- Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The number of oncological patients (OP) admitted to intensive care units (ICU) for sepsis/septic shock has dramatically increased in recent years. The definition of septic shock has been modified, adding hyperlactatemia as a severity biomarker for mortality. However, it remains poorly reported in septic OP. We performed a retrospective analysis from a prospective database of sepsis/septic shock patients admitted to our ICU between September 2017 and September 2019 and followed until day 90. We identified 251 patients and 31.9% had active oncological comorbidity, mainly solid tumor (81.3%). Septic shock criteria were met for 112 (44.6%). Hyperlactatemia was observed in 136 (54.2%) patients and this was associated with a lower survival rate. Overall 90-day mortality was 15.1%. In OP vs. non-OP, hyperlactatemia was more frequent (65% vs. 49.1%,
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