Evidence map›Paper›PMID 33981600›Full record

ArticleFrontiers in oncology2021

Clinical Use of Propranolol Reduces Biomarkers of Proliferation in Gastric Cancer.

Qian Hu, Ping Liao, Wei Li, Jiali Hu, Cuiyu Chen, Yu Zhang, Yang Wang, Ling Chen, Kun Song, Jie Liu and 4 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Therapeutic potential ofFrontiers in pharmacology · 2023
    Article
  9. Article
  10. Dissecting the role of cell signaling versus CD8Journal of molecular medicine (Berlin, Germany) · 2022
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Qian HuDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Ping LiaoDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Wei LiDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Jiali HuDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Cuiyu ChenDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Yu ZhangDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Yang WangDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Ling ChenDepartment of Gastrointestinal Surgery, Xiangya Hospital, Central South University, Changsha, China.
Kun SongDepartment of Gastrointestinal Surgery, Xiangya Hospital, Central South University, Changsha, China.
Jie LiuDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Wei ZhangDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Qing LiDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Howard L McLeodDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.
Yijing HeDepartment of Clinical Pharmacology, Xiangya Hospital, Central South University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer has one of the highest mortality rate in the world, but the treatment is still limited. Building on previous studies, mechanistic studies on propranolol in gastric cancer mice models and gastric cancer patients were performed. Propranolol inhibited the

Indexed as

AKT/MAPKanti-proliferationCD8+ T cellgastricimmunitypropranolol

Identifiers

PMID33981600
PMCPMC8108985

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.