Evidence map›Paper›PMID 33981515›Full record

ArticleCureus2021

Life-Threatening Diffuse Alveolar Hemorrhage as an Initial Presentation of Microscopic Polyangiitis: COVID-19 as a Likely Culprit.

Rutwik Patel, Viralkumar Amrutiya, Moaaz Baghal, Manan Shah, Abraham Lo

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. ANCA vasculitis: A manifestation of Post-Covid-19 Syndrome.Respiratory medicine case reports · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Rutwik PatelInternal Medicine, Hackensack Meridian Health Palisades Medical Center, North Bergen, USA.
Viralkumar AmrutiyaInternal Medicine, Hackensack Meridian Health Palisades Medical Center, North Bergen, USA.
Moaaz BaghalInternal Medicine, Hackensack Meridian Health Palisades Medical Center, North Bergen, USA.
Manan ShahInternal Medicine, Hackensack Meridian Health Palisades Medical Center, North Bergen, USA.
Abraham LoInternal Medicine, Hackensack Meridian Health Palisades Medical Center, North Bergen, USA.
Hackensack Meridian Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microscopic polyangiitis (MPA) is a systemic small vessel vasculitis but it is rare to see life-threatening diffuse alveolar hemorrhage (DAH) in MPA as an initial presentation. MPA more commonly presents with renal involvement and develops pulmonary manifestations later in the disease course. Our patient is a 77-year-old female with a recent history of recovered COVID-19 infection who presented with sudden onset fever, dyspnea, and hemoptysis for three days. She was diagnosed with MPA because of the new-onset DAH, a strongly positive myeloperoxidase (MPO) antibody, and the low likelihood of another etiology. The patient was treated with pulse-dose steroids and plasmapheresis while being on mechanical ventilation. This case highlights the importance of the prompt recognition of DAH as an initial presentation of MPA and illustrates the possible role of COVID-19 in inciting autoimmune conditions.

Indexed as

anti-neutrophil cytoplasmic antibodycovid-19diffuse alveolar hemorrhagemicroscopic polyangiitisvasculitis

Identifiers

PMID33981515
PMCPMC8109046
OpenAlexW3153396991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.