Evidence map›Paper›PMID 33981462›Full record

ArticleCase reports in endocrinology2021

Delayed Calcium Normalization after Successful Parathyroidectomy in Primary Hyperparathyroidism.

Iván Emilio de la Cruz Rodríguez, Elsy Sarahí García Montesinos, María Fernanda Rodríguez-Delgado, Guadalupe Vargas Ortega, Lourdes Balcázar Hernández, Victoria Mendoza Zubieta, Victor Hernández Avendaño, Baldomero González Virla

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Iván Emilio de la Cruz RodríguezEndocrinology Department. Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Mexico City 067200, Mexico.ORCID https://orcid.org/0000-0002-7053-7191
Elsy Sarahí García MontesinosEndocrinology Department. Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Mexico City 067200, Mexico.ORCID https://orcid.org/0000-0002-4645-6332
María Fernanda Rodríguez-DelgadoFaculty of Medicine, Universidad Nacional Autónoma de México, Coordinacion de Servicios a la Comunidad, Programa Comunidad Saludable-Comunidad Solidaria, Mexico City, Mexico.ORCID https://orcid.org/0000-0003-4160-0494
Guadalupe Vargas OrtegaEndocrinology Department. Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Mexico City 067200, Mexico.ORCID https://orcid.org/0000-0002-2225-2925
Lourdes Balcázar HernándezEndocrinology Department. Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Mexico City 067200, Mexico.ORCID https://orcid.org/0000-0002-0373-6641
Victoria Mendoza ZubietaEndocrinology Department. Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Mexico City 067200, Mexico.ORCID https://orcid.org/0000-0001-9601-5204
Victor Hernández AvendañoEndocrinology Department. Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Mexico City 067200, Mexico.ORCID https://orcid.org/0000-0003-2396-6142
Baldomero González VirlaEndocrinology Department. Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Mexico City 067200, Mexico.ORCID https://orcid.org/0000-0001-6924-2209
Centro Medico Nacional Siglo XXI · MXUniversidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionParathyroidectomy is the curative treatment option in primary hyperparathyroidism (PHPT). The decrease of parathormone (PTH) by 50% or more from levels prior to surgery after excision predicts successful parathyroidectomy. Serum calcium is expected to return to normal within 24-72 hours after the surgery; however, nearly 10% have transient, persistent postoperative hypercalcemia. We present a case report of delayed calcium normalization after successful parathyroidectomy in a 38-year-old patient with PHPT.

methodsParathyroidectomy was performed, with evidence of a decrease in PTH levels of more than 50% in the first 24 hours postoperatively compared to presurgical PTH; however, despite curative parathyroidectomy, a delayed calcium normalization was evidenced, with hypercalcemia persistence up to 120 hours postoperatively.

resultsAfter the first month postoperatively, serum calcium remained normal. In conclusion, approximately 10% of patients with curative parathyroidectomy have transient, persistent postoperative hypercalcemia, which is more likely to occur in patients with higher preoperative serum calcium and PTH levels.

conclusionPersistent hypercalcemia after the first month postoperatively is related with persistent PHPT, highlighting the importance of calcium monitoring after parathyroidectomy to predict short-term, medium-term, and long-term outcomes and prognosis.

Identifiers

PMID33981462
PMCPMC8088351
OpenAlexW3158337515

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.